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Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis.
Koldobskiy MA, Jenkinson G, Abante J, Rodriguez DiBlasi VA, Zhou W, Pujadas E, Idrizi A, Tryggvadottir R, Callahan C, Bonifant CL, Rabin KR, Brown PA, Ji H, Goutsias J, Feinberg AP. Koldobskiy MA, et al. Among authors: brown pa. Nat Biomed Eng. 2021 Apr;5(4):360-376. doi: 10.1038/s41551-021-00703-2. Epub 2021 Apr 15. Nat Biomed Eng. 2021. PMID: 33859388 Free PMC article.
Treatment of pediatric acute lymphoblastic leukemia.
Cooper SL, Brown PA. Cooper SL, et al. Among authors: brown pa. Pediatr Clin North Am. 2015 Feb;62(1):61-73. doi: 10.1016/j.pcl.2014.09.006. Epub 2014 Oct 18. Pediatr Clin North Am. 2015. PMID: 25435112 Free PMC article. Review.
A phase 1 dosing study of ruxolitinib in children with relapsed or refractory solid tumors, leukemias, or myeloproliferative neoplasms: A Children's Oncology Group phase 1 consortium study (ADVL1011).
Loh ML, Tasian SK, Rabin KR, Brown P, Magoon D, Reid JM, Chen X, Ahern CH, Weigel BJ, Blaney SM. Loh ML, et al. Pediatr Blood Cancer. 2015 Oct;62(10):1717-24. doi: 10.1002/pbc.25575. Epub 2015 May 13. Pediatr Blood Cancer. 2015. PMID: 25976292 Free PMC article. Clinical Trial.
Evolution of the Epigenetic Landscape in Childhood B Acute Lymphoblastic Leukemia and Its Role in Drug Resistance.
Saint Fleur-Lominy S, Evensen NA, Bhatla T, Sethia G, Narang S, Choi JH, Ma X, Yang JJ, Kelly S, Raetz E, Harvey RC, Willman C, Loh ML, Hunger SP, Brown PA, Getz KM, Meydan C, Mason CE, Tsirigos A, Carroll WL. Saint Fleur-Lominy S, et al. Among authors: brown pa. Cancer Res. 2020 Dec 1;80(23):5189-5202. doi: 10.1158/0008-5472.CAN-20-1145. Epub 2020 Oct 16. Cancer Res. 2020. PMID: 33067268 Free PMC article.
Racial and ethnic disparities in childhood and young adult acute lymphocytic leukaemia: secondary analyses of eight Children's Oncology Group cohort trials.
Gupta S, Dai Y, Chen Z, Winestone LE, Teachey DT, Bona K, Aplenc R, Rabin KR, Zweidler-McKay P, Carroll AJ, Heerema NA, Gastier-Foster J, Borowitz MJ, Wood BL, Maloney KW, Mattano LA Jr, Larsen EC, Angiolillo AL, Burke MJ, Salzer WL, Winter SS, Brown PA, Guest EM, Dunsmore KP, Kairalla JA, Winick NJ, Carroll WL, Raetz EA, Hunger SP, Loh ML, Devidas M. Gupta S, et al. Among authors: brown pa. Lancet Haematol. 2023 Feb;10(2):e129-e141. doi: 10.1016/S2352-3026(22)00371-4. Lancet Haematol. 2023. PMID: 36725118 Free PMC article.
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor MJ, Johns C, Chicas A, Mulloy JC, Kogan SC, Brown P, Valent P, Bradner JE, Lowe SW, Vakoc CR. Zuber J, et al. Nature. 2011 Aug 3;478(7370):524-8. doi: 10.1038/nature10334. Nature. 2011. PMID: 21814200 Free PMC article.
327 results