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Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer's disease.
Crist AM, Hinkle KM, Wang X, Moloney CM, Matchett BJ, Labuzan SA, Frankenhauser I, Azu NO, Liesinger AM, Lesser ER, Serie DJ, Quicksall ZS, Patel TA, Carnwath TP, DeTure M, Tang X, Petersen RC, Duara R, Graff-Radford NR, Allen M, Carrasquillo MM, Li H, Ross OA, Ertekin-Taner N, Dickson DW, Asmann YW, Carter RE, Murray ME. Crist AM, et al. Among authors: li h. Nat Commun. 2021 Apr 19;12(1):2311. doi: 10.1038/s41467-021-22399-3. Nat Commun. 2021. PMID: 33875655 Free PMC article.
Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS.
Prudencio M, Belzil VV, Batra R, Ross CA, Gendron TF, Pregent LJ, Murray ME, Overstreet KK, Piazza-Johnston AE, Desaro P, Bieniek KF, DeTure M, Lee WC, Biendarra SM, Davis MD, Baker MC, Perkerson RB, van Blitterswijk M, Stetler CT, Rademakers R, Link CD, Dickson DW, Boylan KB, Li H, Petrucelli L. Prudencio M, et al. Among authors: li h. Nat Neurosci. 2015 Aug;18(8):1175-82. doi: 10.1038/nn.4065. Epub 2015 Jul 20. Nat Neurosci. 2015. PMID: 26192745 Free PMC article.
Conserved DNA methylation combined with differential frontal cortex and cerebellar expression distinguishes C9orf72-associated and sporadic ALS, and implicates SERPINA1 in disease.
Ebbert MTW, Ross CA, Pregent LJ, Lank RJ, Zhang C, Katzman RB, Jansen-West K, Song Y, da Rocha EL, Palmucci C, Desaro P, Robertson AE, Caputo AM, Dickson DW, Boylan KB, Rademakers R, Ordog T, Li H, Belzil VV. Ebbert MTW, et al. Among authors: li h. Acta Neuropathol. 2017 Nov;134(5):715-728. doi: 10.1007/s00401-017-1760-4. Epub 2017 Aug 14. Acta Neuropathol. 2017. PMID: 28808785 Free PMC article.
Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo.
Apicco DJ, Ash PEA, Maziuk B, LeBlang C, Medalla M, Al Abdullatif A, Ferragud A, Botelho E, Ballance HI, Dhawan U, Boudeau S, Cruz AL, Kashy D, Wong A, Goldberg LR, Yazdani N, Zhang C, Ung CY, Tripodis Y, Kanaan NM, Ikezu T, Cottone P, Leszyk J, Li H, Luebke J, Bryant CD, Wolozin B. Apicco DJ, et al. Among authors: li h. Nat Neurosci. 2018 Jan;21(1):72-80. doi: 10.1038/s41593-017-0022-z. Epub 2017 Nov 20. Nat Neurosci. 2018. PMID: 29273772 Free PMC article.
Reconstruction of complex single-cell trajectories using CellRouter.
Lummertz da Rocha E, Rowe RG, Lundin V, Malleshaiah M, Jha DK, Rambo CR, Li H, North TE, Collins JJ, Daley GQ. Lummertz da Rocha E, et al. Among authors: li h. Nat Commun. 2018 Mar 1;9(1):892. doi: 10.1038/s41467-018-03214-y. Nat Commun. 2018. PMID: 29497036 Free PMC article.
RNA binding proteins co-localize with small tau inclusions in tauopathy.
Maziuk BF, Apicco DJ, Cruz AL, Jiang L, Ash PEA, da Rocha EL, Zhang C, Yu WH, Leszyk J, Abisambra JF, Li H, Wolozin B. Maziuk BF, et al. Among authors: li h. Acta Neuropathol Commun. 2018 Aug 1;6(1):71. doi: 10.1186/s40478-018-0574-5. Acta Neuropathol Commun. 2018. PMID: 30068389 Free PMC article.
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy.
Jiang L, Lin W, Zhang C, Ash PEA, Verma M, Kwan J, van Vliet E, Yang Z, Cruz AL, Boudeau S, Maziuk BF, Lei S, Song J, Alvarez VE, Hovde S, Abisambra JF, Kuo MH, Kanaan N, Murray ME, Crary JF, Zhao J, Cheng JX, Petrucelli L, Li H, Emili A, Wolozin B. Jiang L, et al. Among authors: li h. Mol Cell. 2021 Oct 21;81(20):4209-4227.e12. doi: 10.1016/j.molcel.2021.07.038. Epub 2021 Aug 27. Mol Cell. 2021. PMID: 34453888 Free PMC article.
Hyperphosphorylated PTEN exerts oncogenic properties.
van Ree JH, Jeganathan KB, Fierro Velasco RO, Zhang C, Can I, Hamada M, Li H, Baker DJ, van Deursen JM. van Ree JH, et al. Among authors: li h. Nat Commun. 2023 May 24;14(1):2983. doi: 10.1038/s41467-023-38740-x. Nat Commun. 2023. PMID: 37225693 Free PMC article.
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