Roybal KT - Search Results

1

SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma.

Choe JH, Watchmaker PB, Simic MS, Gilbert RD, Li AW, Krasnow NA, Downey KM, Yu W, Carrera DA, Celli A, Cho J, Briones JD, Duecker JM, Goretsky YE, Dannenfelser R, Cardarelli L, Troyanskaya O, Sidhu SS, Roybal KT, Okada H, Lim WA. Choe JH, et al. Among authors: roybal kt. Sci Transl Med. 2021 Apr 28;13(591):eabe7378. doi: 10.1126/scitranslmed.abe7378. Sci Transl Med. 2021. PMID: 33910979 Free PMC article.

2

Synthetic biology approaches to engineer T cells.

Wu CY, Rupp LJ, Roybal KT, Lim WA. Wu CY, et al. Among authors: roybal kt. Curr Opin Immunol. 2015 Aug;35:123-30. doi: 10.1016/j.coi.2015.06.015. Epub 2015 Jul 25. Curr Opin Immunol. 2015. PMID: 26218616 Free PMC article. Review.

3

Remote control of therapeutic T cells through a small molecule-gated chimeric receptor.

Wu CY, Roybal KT, Puchner EM, Onuffer J, Lim WA. Wu CY, et al. Among authors: roybal kt. Science. 2015 Oct 16;350(6258):aab4077. doi: 10.1126/science.aab4077. Epub 2015 Sep 24. Science. 2015. PMID: 26405231 Free PMC article.

4

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors.

Morsut L, Roybal KT, Xiong X, Gordley RM, Coyle SM, Thomson M, Lim WA. Morsut L, et al. Among authors: roybal kt. Cell. 2016 Feb 11;164(4):780-91. doi: 10.1016/j.cell.2016.01.012. Epub 2016 Jan 28. Cell. 2016. PMID: 26830878 Free PMC article.

5

Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits.

Roybal KT, Rupp LJ, Morsut L, Walker WJ, McNally KA, Park JS, Lim WA. Roybal KT, et al. Cell. 2016 Feb 11;164(4):770-9. doi: 10.1016/j.cell.2016.01.011. Epub 2016 Jan 28. Cell. 2016. PMID: 26830879 Free PMC article.

6

Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors.

Roybal KT, Williams JZ, Morsut L, Rupp LJ, Kolinko I, Choe JH, Walker WJ, McNally KA, Lim WA. Roybal KT, et al. Cell. 2016 Oct 6;167(2):419-432.e16. doi: 10.1016/j.cell.2016.09.011. Epub 2016 Sep 29. Cell. 2016. PMID: 27693353 Free PMC article.

7

CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells.

Rupp LJ, Schumann K, Roybal KT, Gate RE, Ye CJ, Lim WA, Marson A. Rupp LJ, et al. Among authors: roybal kt. Sci Rep. 2017 Apr 7;7(1):737. doi: 10.1038/s41598-017-00462-8. Sci Rep. 2017. PMID: 28389661 Free PMC article.

8

Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities.

Roybal KT, Lim WA. Roybal KT, et al. Annu Rev Immunol. 2017 Apr 26;35:229-253. doi: 10.1146/annurev-immunol-051116-052302. Annu Rev Immunol. 2017. PMID: 28446063 Free PMC article. Review.

9

Paving New Roads for CARs.

Hyrenius-Wittsten A, Roybal KT. Hyrenius-Wittsten A, et al. Among authors: roybal kt. Trends Cancer. 2019 Oct;5(10):583-592. doi: 10.1016/j.trecan.2019.09.005. Epub 2019 Oct 19. Trends Cancer. 2019. PMID: 31706506 Review.

10

Precise T cell recognition programs designed by transcriptionally linking multiple receptors.

Williams JZ, Allen GM, Shah D, Sterin IS, Kim KH, Garcia VP, Shavey GE, Yu W, Puig-Saus C, Tsoi J, Ribas A, Roybal KT, Lim WA. Williams JZ, et al. Among authors: roybal kt. Science. 2020 Nov 27;370(6520):1099-1104. doi: 10.1126/science.abc6270. Science. 2020. PMID: 33243890 Free PMC article.

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