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SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma.
Choe JH, Watchmaker PB, Simic MS, Gilbert RD, Li AW, Krasnow NA, Downey KM, Yu W, Carrera DA, Celli A, Cho J, Briones JD, Duecker JM, Goretsky YE, Dannenfelser R, Cardarelli L, Troyanskaya O, Sidhu SS, Roybal KT, Okada H, Lim WA. Choe JH, et al. Among authors: simic ms. Sci Transl Med. 2021 Apr 28;13(591):eabe7378. doi: 10.1126/scitranslmed.abe7378. Sci Transl Med. 2021. PMID: 33910979 Free PMC article.
CAR-T Cell-Mediated B-Cell Depletion in Central Nervous System Autoimmunity.
Gupta S, Simic M, Sagan SA, Shepherd C, Duecker J, Sobel RA, Dandekar R, Wu GF, Wu W, Pak JE, Hauser SL, Lim W, Wilson MR, Zamvil SS. Gupta S, et al. Neurol Neuroimmunol Neuroinflamm. 2023 Jan 19;10(2):e200080. doi: 10.1212/NXI.0000000000200080. Print 2023 Mar. Neurol Neuroimmunol Neuroinflamm. 2023. PMID: 36657993 Free PMC article.
The Lysosome, Elixir of Neural Stem Cell Youth.
Simic MS, Dillin A. Simic MS, et al. Cell Stem Cell. 2018 May 3;22(5):619-620. doi: 10.1016/j.stem.2018.04.017. Cell Stem Cell. 2018. PMID: 29727677 Free article.
The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPRER.
Schinzel RT, Higuchi-Sanabria R, Shalem O, Moehle EA, Webster BM, Joe L, Bar-Ziv R, Frankino PA, Durieux J, Pender C, Kelet N, Kumar SS, Savalia N, Chi H, Simic M, Nguyen NT, Dillin A. Schinzel RT, et al. Cell. 2019 Nov 27;179(6):1306-1318.e18. doi: 10.1016/j.cell.2019.10.018. Epub 2019 Nov 21. Cell. 2019. PMID: 31761535 Free PMC article.
Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response.
Kim HE, Grant AR, Simic MS, Kohnz RA, Nomura DK, Durieux J, Riera CE, Sanchez M, Kapernick E, Wolff S, Dillin A. Kim HE, et al. Among authors: simic ms. Cell. 2016 Sep 8;166(6):1539-1552.e16. doi: 10.1016/j.cell.2016.08.027. Cell. 2016. PMID: 27610574 Free PMC article.
Proteostasis and aging of stem cells.
Vilchez D, Simic MS, Dillin A. Vilchez D, et al. Among authors: simic ms. Trends Cell Biol. 2014 Mar;24(3):161-70. doi: 10.1016/j.tcb.2013.09.002. Epub 2013 Oct 3. Trends Cell Biol. 2014. PMID: 24094931 Review.
12 results