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FYN-TRAF3IP2 induces NF-κB signaling-driven peripheral T cell lymphoma.
Moon CS, Reglero C, Cortes JR, Quinn SA, Alvarez S, Zhao J, Lin WW, Cooke AJ, Abate F, Soderquist CR, Fiñana C, Inghirami G, Campo E, Bhagat G, Rabadan R, Palomero T, Ferrando AA. Moon CS, et al. Among authors: ferrando aa. Nat Cancer. 2021 Jan;2(1):98-113. doi: 10.1038/s43018-020-00161-w. Epub 2021 Jan 13. Nat Cancer. 2021. PMID: 33928261 Free PMC article.
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
Palomero T, Lim WK, Odom DT, Sulis ML, Real PJ, Margolin A, Barnes KC, O'Neil J, Neuberg D, Weng AP, Aster JC, Sigaux F, Soulier J, Look AT, Young RA, Califano A, Ferrando AA. Palomero T, et al. Among authors: ferrando aa. Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18261-6. doi: 10.1073/pnas.0606108103. Epub 2006 Nov 17. Proc Natl Acad Sci U S A. 2006. PMID: 17114293 Free PMC article.
Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.
Vilimas T, Mascarenhas J, Palomero T, Mandal M, Buonamici S, Meng F, Thompson B, Spaulding C, Macaroun S, Alegre ML, Kee BL, Ferrando A, Miele L, Aifantis I. Vilimas T, et al. Nat Med. 2007 Jan;13(1):70-7. doi: 10.1038/nm1524. Epub 2006 Dec 17. Nat Med. 2007. PMID: 17173050
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Palomero T, Sulis ML, Cortina M, Real PJ, Barnes K, Ciofani M, Caparros E, Buteau J, Brown K, Perkins SL, Bhagat G, Agarwal AM, Basso G, Castillo M, Nagase S, Cordon-Cardo C, Parsons R, Zúñiga-Pflücker JC, Dominguez M, Ferrando AA. Palomero T, et al. Among authors: ferrando aa. Nat Med. 2007 Oct;13(10):1203-10. doi: 10.1038/nm1636. Epub 2007 Sep 16. Nat Med. 2007. PMID: 17873882 Free PMC article.
NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL.
Sulis ML, Williams O, Palomero T, Tosello V, Pallikuppam S, Real PJ, Barnes K, Zuurbier L, Meijerink JP, Ferrando AA. Sulis ML, et al. Among authors: ferrando aa. Blood. 2008 Aug 1;112(3):733-40. doi: 10.1182/blood-2007-12-130096. Epub 2008 Apr 14. Blood. 2008. PMID: 18411416 Free PMC article.
264 results