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Evaluation of polygenic prediction methodology within a reference-standardized framework.
Pain O, Glanville KP, Hagenaars SP, Selzam S, Fürtjes AE, Gaspar HA, Coleman JRI, Rimfeld K, Breen G, Plomin R, Folkersen L, Lewis CM. Pain O, et al. Among authors: hagenaars sp. PLoS Genet. 2021 May 4;17(5):e1009021. doi: 10.1371/journal.pgen.1009021. eCollection 2021 May. PLoS Genet. 2021. PMID: 33945532 Free PMC article.
Genetic contributions to Trail Making Test performance in UK Biobank.
Hagenaars SP, Cox SR, Hill WD, Davies G, Liewald DCM; CHARGE consortium Cognitive Working Group; Harris SE, McIntosh AM, Gale CR, Deary IJ. Hagenaars SP, et al. Mol Psychiatry. 2018 Jul;23(7):1575-1583. doi: 10.1038/mp.2017.189. Epub 2017 Sep 19. Mol Psychiatry. 2018. PMID: 28924184
Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism.
Luciano M, Hagenaars SP, Davies G, Hill WD, Clarke TK, Shirali M, Harris SE, Marioni RE, Liewald DC, Fawns-Ritchie C, Adams MJ, Howard DM, Lewis CM, Gale CR, McIntosh AM, Deary IJ. Luciano M, et al. Among authors: hagenaars sp. Nat Genet. 2018 Jan;50(1):6-11. doi: 10.1038/s41588-017-0013-8. Epub 2017 Dec 18. Nat Genet. 2018. PMID: 29255261 Free PMC article.
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.
Howard DM, Adams MJ, Shirali M, Clarke TK, Marioni RE, Davies G, Coleman JRI, Alloza C, Shen X, Barbu MC, Wigmore EM, Gibson J; 23andMe Research Team; Hagenaars SP, Lewis CM, Ward J, Smith DJ, Sullivan PF, Haley CS, Breen G, Deary IJ, McIntosh AM. Howard DM, et al. Among authors: hagenaars sp. Nat Commun. 2018 Apr 16;9(1):1470. doi: 10.1038/s41467-018-03819-3. Nat Commun. 2018. PMID: 29662059 Free PMC article.
Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.
Howard DM, Adams MJ, Shirali M, Clarke TK, Marioni RE, Davies G, Coleman JRI, Alloza C, Shen X, Barbu MC, Wigmore EM, Gibson J, Hagenaars SP, Lewis CM, Ward J, Smith DJ, Sullivan PF, Haley CS, Breen G, Deary IJ, McIntosh AM. Howard DM, et al. Among authors: hagenaars sp. Nat Commun. 2018 Aug 30;9(1):3578. doi: 10.1038/s41467-018-05310-5. Nat Commun. 2018. PMID: 30166530 Free PMC article. No abstract available.
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
Howard DM, Adams MJ, Clarke TK, Hafferty JD, Gibson J, Shirali M, Coleman JRI, Hagenaars SP, Ward J, Wigmore EM, Alloza C, Shen X, Barbu MC, Xu EY, Whalley HC, Marioni RE, Porteous DJ, Davies G, Deary IJ, Hemani G, Berger K, Teismann H, Rawal R, Arolt V, Baune BT, Dannlowski U, Domschke K, Tian C, Hinds DA; 23andMe Research Team; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Trzaskowski M, Byrne EM, Ripke S, Smith DJ, Sullivan PF, Wray NR, Breen G, Lewis CM, McIntosh AM. Howard DM, et al. Among authors: hagenaars sp. Nat Neurosci. 2019 Mar;22(3):343-352. doi: 10.1038/s41593-018-0326-7. Epub 2019 Feb 4. Nat Neurosci. 2019. PMID: 30718901 Free PMC article.
Polygenic predictors of age-related decline in cognitive ability.
Ritchie SJ, Hill WD, Marioni RE, Davies G, Hagenaars SP, Harris SE, Cox SR, Taylor AM, Corley J, Pattie A, Redmond P, Starr JM, Deary IJ. Ritchie SJ, et al. Among authors: hagenaars sp. Mol Psychiatry. 2020 Oct;25(10):2584-2598. doi: 10.1038/s41380-019-0372-x. Epub 2019 Feb 13. Mol Psychiatry. 2020. PMID: 30760887 Free PMC article.
80 results