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In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity.
Cousens LP, Najafian N, Mingozzi F, Elyaman W, Mazer B, Moise L, Messitt TJ, Su Y, Sayegh M, High K, Khoury SJ, Scott DW, De Groot AS. Cousens LP, et al. Among authors: de groot as. J Clin Immunol. 2013 Jan;33 Suppl 1(Suppl 1):S43-9. doi: 10.1007/s10875-012-9762-4. Epub 2012 Sep 2. J Clin Immunol. 2013. PMID: 22941509 Free PMC article. Review.
Tregitope update: mechanism of action parallels IVIg.
Cousens LP, Tassone R, Mazer BD, Ramachandiran V, Scott DW, De Groot AS. Cousens LP, et al. Among authors: de groot as. Autoimmun Rev. 2013 Jan;12(3):436-43. doi: 10.1016/j.autrev.2012.08.017. Epub 2012 Aug 28. Autoimmun Rev. 2013. PMID: 22944299 Free article. Review.
Tregitope peptides: the active pharmaceutical ingredient of IVIG?
De Groot AS, Cousens L, Mingozzi F, Martin W. De Groot AS, et al. Clin Dev Immunol. 2013;2013:493138. doi: 10.1155/2013/493138. Epub 2013 Dec 25. Clin Dev Immunol. 2013. PMID: 24454476 Free PMC article. Review.
Five years ago, we reported the identification and characterization of several regulatory T-cell epitopes (now called Tregitopes) that were discovered in the heavy and light chains of IgG (De Groot et al. Blood, 2008). When added ex vivo to human PBMCs, these Tregit …
Five years ago, we reported the identification and characterization of several regulatory T-cell epitopes (now called Tregitopes) that were …
Tregitope: Immunomodulation powerhouse.
Cousens L, Najafian N, Martin WD, De Groot AS. Cousens L, et al. Among authors: de groot as. Hum Immunol. 2014 Dec;75(12):1139-46. doi: 10.1016/j.humimm.2014.10.012. Epub 2014 Oct 22. Hum Immunol. 2014. PMID: 25454619 Free article.
Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine.
Scholzen A, Richard G, Moise L, Baeten LA, Reeves PM, Martin WD, Brauns TA, Boyle CM, Raju Paul S, Bucala R, Bowen RA, Garritsen A, De Groot AS, Sluder AE, Poznansky MC. Scholzen A, et al. Among authors: de groot as. Front Immunol. 2019 Feb 15;10:207. doi: 10.3389/fimmu.2019.00207. eCollection 2019. Front Immunol. 2019. PMID: 30828331 Free PMC article.
Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools.
De Groot AS, Moise L, Terry F, Gutierrez AH, Hindocha P, Richard G, Hoft DF, Ross TM, Noe AR, Takahashi Y, Kotraiah V, Silk SE, Nielsen CM, Minassian AM, Ashfield R, Ardito M, Draper SJ, Martin WD. De Groot AS, et al. Front Immunol. 2020 Apr 7;11:442. doi: 10.3389/fimmu.2020.00442. eCollection 2020. Front Immunol. 2020. PMID: 32318055 Free PMC article. Review.
228 results