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Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain.
Navia-Pelaez JM, Choi SH, Dos Santos Aggum Capettini L, Xia Y, Gonen A, Agatisa-Boyle C, Delay L, Gonçalves Dos Santos G, Catroli GF, Kim J, Lu JW, Saylor B, Winkels H, Durant CP, Ghosheh Y, Beaton G, Ley K, Kufareva I, Corr M, Yaksh TL, Miller YI. Navia-Pelaez JM, et al. Among authors: gonen a. J Exp Med. 2021 Jul 5;218(7):e20202059. doi: 10.1084/jem.20202059. Epub 2021 May 10. J Exp Med. 2021. PMID: 33970188 Free PMC article.
MD-2 binds cholesterol.
Choi SH, Kim J, Gonen A, Viriyakosol S, Miller YI. Choi SH, et al. Among authors: gonen a. Biochem Biophys Res Commun. 2016 Feb 19;470(4):877-80. doi: 10.1016/j.bbrc.2016.01.126. Epub 2016 Jan 22. Biochem Biophys Res Commun. 2016. PMID: 26806306 Free PMC article.
Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1: possible mechanism for acceleration of atherosclerosis by subclinical endotoxemia.
Wiesner P, Choi SH, Almazan F, Benner C, Huang W, Diehl CJ, Gonen A, Butler S, Witztum JL, Glass CK, Miller YI. Wiesner P, et al. Among authors: gonen a. Circ Res. 2010 Jul 9;107(1):56-65. doi: 10.1161/CIRCRESAHA.110.218420. Epub 2010 May 20. Circ Res. 2010. PMID: 20489162 Free PMC article.
Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.
Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. Que X, et al. Among authors: gonen a. Nature. 2018 Jun;558(7709):301-306. doi: 10.1038/s41586-018-0198-8. Epub 2018 Jun 6. Nature. 2018. PMID: 29875409 Free PMC article.
Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity.
Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K, Boullier A, Gonen A, Diehl CJ, Que X, Montano E, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. Miller YI, et al. Among authors: gonen a. Circ Res. 2011 Jan 21;108(2):235-48. doi: 10.1161/CIRCRESAHA.110.223875. Circ Res. 2011. PMID: 21252151 Free PMC article. Review.
64 results