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MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration.
Simone R, Javad F, Emmett W, Wilkins OG, Almeida FL, Barahona-Torres N, Zareba-Paslawska J, Ehteramyan M, Zuccotti P, Modelska A, Siva K, Virdi GS, Mitchell JS, Harley J, Kay VA, Hondhamuni G, Trabzuni D, Ryten M, Wray S, Preza E, Kia DA, Pittman A, Ferrari R, Manzoni C, Lees A, Hardy JA, Denti MA, Quattrone A, Patani R, Svenningsson P, Warner TT, Plagnol V, Ule J, de Silva R. Simone R, et al. Among authors: ule j. Nature. 2021 Jun;594(7861):117-123. doi: 10.1038/s41586-021-03556-6. Epub 2021 May 19. Nature. 2021. PMID: 34012113 Free PMC article.
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.
Tollervey JR, Curk T, Rogelj B, Briese M, Cereda M, Kayikci M, König J, Hortobágyi T, Nishimura AL, Zupunski V, Patani R, Chandran S, Rot G, Zupan B, Shaw CE, Ule J. Tollervey JR, et al. Among authors: ule j. Nat Neurosci. 2011 Apr;14(4):452-8. doi: 10.1038/nn.2778. Epub 2011 Feb 27. Nat Neurosci. 2011. PMID: 21358640 Free PMC article.
Recursive splicing in long vertebrate genes.
Sibley CR, Emmett W, Blazquez L, Faro A, Haberman N, Briese M, Trabzuni D, Ryten M, Weale ME, Hardy J, Modic M, Curk T, Wilson SW, Plagnol V, Ule J. Sibley CR, et al. Among authors: ule j. Nature. 2015 May 21;521(7552):371-375. doi: 10.1038/nature14466. Epub 2015 May 13. Nature. 2015. PMID: 25970246 Free PMC article.
Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS.
Hall CE, Yao Z, Choi M, Tyzack GE, Serio A, Luisier R, Harley J, Preza E, Arber C, Crisp SJ, Watson PMD, Kullmann DM, Abramov AY, Wray S, Burley R, Loh SHY, Martins LM, Stevens MM, Luscombe NM, Sibley CR, Lakatos A, Ule J, Gandhi S, Patani R. Hall CE, et al. Among authors: ule j. Cell Rep. 2017 May 30;19(9):1739-1749. doi: 10.1016/j.celrep.2017.05.024. Cell Rep. 2017. PMID: 28564594 Free PMC article.
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS.
Luisier R, Tyzack GE, Hall CE, Mitchell JS, Devine H, Taha DM, Malik B, Meyer I, Greensmith L, Newcombe J, Ule J, Luscombe NM, Patani R. Luisier R, et al. Among authors: ule j. Nat Commun. 2018 May 22;9(1):2010. doi: 10.1038/s41467-018-04373-8. Nat Commun. 2018. PMID: 29789581 Free PMC article.
Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing.
Attig J, Agostini F, Gooding C, Chakrabarti AM, Singh A, Haberman N, Zagalak JA, Emmett W, Smith CWJ, Luscombe NM, Ule J. Attig J, et al. Among authors: ule j. Cell. 2018 Aug 23;174(5):1067-1081.e17. doi: 10.1016/j.cell.2018.07.001. Epub 2018 Aug 2. Cell. 2018. PMID: 30078707 Free PMC article.
162 results