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Genetics of the human metabolome, what is next?
Dharuri H, Demirkan A, van Klinken JB, Mook-Kanamori DO, van Duijn CM, 't Hoen PA, Willems van Dijk K. Dharuri H, et al. Among authors: van duijn cm, willems van dijk k, van klinken jb. Biochim Biophys Acta. 2014 Oct;1842(10):1923-1931. doi: 10.1016/j.bbadis.2014.05.030. Epub 2014 Jun 4. Biochim Biophys Acta. 2014. PMID: 24905732 Free article. Review.
Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.
van Leeuwen EM, Sabo A, Bis JC, Huffman JE, Manichaikul A, Smith AV, Feitosa MF, Demissie S, Joshi PK, Duan Q, Marten J, van Klinken JB, Surakka I, Nolte IM, Zhang W, Mbarek H, Li-Gao R, Trompet S, Verweij N, Evangelou E, Lyytikäinen LP, Tayo BO, Deelen J, van der Most PJ, van der Laan SW, Arking DE, Morrison A, Dehghan A, Franco OH, Hofman A, Rivadeneira F, Sijbrands EJ, Uitterlinden AG, Mychaleckyj JC, Campbell A, Hocking LJ, Padmanabhan S, Brody JA, Rice KM, White CC, Harris T, Isaacs A, Campbell H, Lange LA, Rudan I, Kolcic I, Navarro P, Zemunik T, Salomaa V; LifeLines Cohort Study; Kooner AS, Kooner JS, Lehne B, Scott WR, Tan ST, de Geus EJ, Milaneschi Y, Penninx BW, Willemsen G, de Mutsert R, Ford I, Gansevoort RT, Segura-Lepe MP, Raitakari OT, Viikari JS, Nikus K, Forrester T, McKenzie CA, de Craen AJ, de Ruijter HM; CHARGE Lipids Working Group; Pasterkamp G, Snieder H, Oldehinkel AJ, Slagboom PE, Cooper RS, Kähönen M, Lehtimäki T, Elliott P, van der Harst P, Jukema JW, Mook-Kanamori DO, Boomsma DI, Chambers JC, Swertz M, Ripatti S, Willems van Dijk K, Vitart V, Polasek O, Hayward C, Wilson JG, Wilson JF, Gudnason V, Rich SS, Psaty … See abstract for full author list ➔ van Leeuwen EM, et al. Among authors: van duijn cm, willems van dijk k, van der harst p, van klinken jb, van der laan sw, van der most pj. J Med Genet. 2016 Jul;53(7):441-9. doi: 10.1136/jmedgenet-2015-103439. Epub 2016 Apr 1. J Med Genet. 2016. PMID: 27036123 Free PMC article.
Interrelationship of the rs7903146 TCF7L2 gene variant with measures of glucose metabolism and adiposity: The NEO study.
Noordam R, Zwetsloot CPA, de Mutsert R, Mook-Kanamori DO, Lamb HJ, de Roos A, de Koning EJP, Rosendaal FR, Willems van Dijk K, van Heemst D. Noordam R, et al. Among authors: van heemst d, willems van dijk k. Nutr Metab Cardiovasc Dis. 2018 Feb;28(2):150-157. doi: 10.1016/j.numecd.2017.10.012. Epub 2017 Oct 18. Nutr Metab Cardiovasc Dis. 2018. PMID: 29174029
Postprandial metabolite profiles associated with type 2 diabetes clearly stratify individuals with impaired fasting glucose.
Li-Gao R, de Mutsert R, Rensen PCN, van Klinken JB, Prehn C, Adamski J, van Hylckama Vlieg A, den Heijer M, le Cessie S, Rosendaal FR, Willems van Dijk K, Mook-Kanamori DO. Li-Gao R, et al. Among authors: willems van dijk k, van klinken jb, van hylckama vlieg a. Metabolomics. 2018;14(1):13. doi: 10.1007/s11306-017-1307-7. Epub 2017 Dec 12. Metabolomics. 2018. PMID: 29249917 Free PMC article.
Relation of Overall and Abdominal Adiposity With Electrocardiogram Parameters of Subclinical Cardiovascular Disease in Individuals Aged 45 to 65 Years (from the Netherlands Epidemiology of Obesity Study).
Elffers TW, de Mutsert R, Lamb HJ, Maan AC, Macfarlane PW, Willems van Dijk K, Rosendaal FR, Jukema JW, Trompet S. Elffers TW, et al. Among authors: willems van dijk k. Am J Cardiol. 2018 Mar 1;121(5):570-578. doi: 10.1016/j.amjcard.2017.11.030. Epub 2017 Dec 11. Am J Cardiol. 2018. PMID: 29310809 Free article.
Genetics of fasting and postprandial metabolite levels are overlapping.
Li-Gao R, de Mutsert R, Rosendaal FR, Willems van Dijk K, Mook-Kanamori DO. Li-Gao R, et al. Among authors: willems van dijk k. Physiol Genomics. 2018 Apr 1;50(4):235-236. doi: 10.1152/physiolgenomics.00101.2017. Epub 2018 Jan 26. Physiol Genomics. 2018. PMID: 29373077 Free PMC article.
133 results