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Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels.
Autophagy. 2021 Dec;17(12):4119-4140. doi: 10.1080/15548627.2021.1904489. Epub 2021 May 24.
Autophagy. 2021.
PMID: 34024231
Free PMC article.
FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16INK4a increase.
Voisin J, Farina F, Naphade S, Fontaine M, Tshilenge KT, Galicia Aguirre C, Lopez-Ramirez A, Dancourt J, Ginisty A, Sasidharan Nair S, Lakshika Madushani K, Zhang N, Lejeune FX, Verny M, Campisi J, Ellerby LM, Neri C.
Voisin J, et al. Among authors: lakshika madushani k.
Aging Cell. 2020 Nov;19(11):e13226. doi: 10.1111/acel.13226. Epub 2020 Nov 6.
Aging Cell. 2020.
PMID: 33156570
Free PMC article.
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