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A KCNK16 mutation causing TALK-1 gain of function is associated with maturity-onset diabetes of the young.
JCI Insight. 2021 Jul 8;6(13):e138057. doi: 10.1172/jci.insight.138057.
JCI Insight. 2021.
PMID: 34032641
Free PMC article.
Lactate activation of α-cell KATP channels inhibits glucagon secretion by hyperpolarizing the membrane potential and reducing Ca2+ entry.
Zaborska KE, Dadi PK, Dickerson MT, Nakhe AY, Thorson AS, Schaub CM, Graff SM, Stanley JE, Kondapavuluru RS, Denton JS, Jacobson DA.
Zaborska KE, et al. Among authors: schaub cm.
Mol Metab. 2020 Dec;42:101056. doi: 10.1016/j.molmet.2020.101056. Epub 2020 Jul 28.
Mol Metab. 2020.
PMID: 32736089
Free PMC article.
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Tetraspanin-7 regulation of L-type voltage-dependent calcium channels controls pancreatic β-cell insulin secretion.
Dickerson MT, Dadi PK, Butterworth RB, Nakhe AY, Graff SM, Zaborska KE, Schaub CM, Jacobson DA.
Dickerson MT, et al. Among authors: schaub cm.
J Physiol. 2020 Nov;598(21):4887-4905. doi: 10.1113/JP279941. Epub 2020 Sep 1.
J Physiol. 2020.
PMID: 32790176
Free PMC article.
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TRPM7 is a crucial regulator of pancreatic endocrine development and high-fat-diet-induced β-cell proliferation.
Altman MK, Schaub CM, Dadi PK, Dickerson MT, Zaborska KE, Nakhe AY, Graff SM, Galletta TJ, Amarnath G, Thorson AS, Gu G, Jacobson DA.
Altman MK, et al. Among authors: schaub cm.
Development. 2021 Aug 15;148(16):dev194928. doi: 10.1242/dev.194928. Epub 2021 Aug 16.
Development. 2021.
PMID: 34345920
Free PMC article.
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Liraglutide increases islet Ca2+ oscillation frequency and insulin secretion by activating hyperpolarization-activated cyclic nucleotide-gated channels.
Zaborska KE, Jordan KL, Thorson AS, Dadi PK, Schaub CM, Nakhe AY, Dickerson MT, Lynch JC, Weiss AJ, Dobson JR, Jacobson DA.
Zaborska KE, et al. Among authors: schaub cm.
Diabetes Obes Metab. 2022 Sep;24(9):1741-1752. doi: 10.1111/dom.14747. Epub 2022 May 30.
Diabetes Obes Metab. 2022.
PMID: 35546791
Free PMC article.
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Gi/o protein-coupled receptor inhibition of beta-cell electrical excitability and insulin secretion depends on Na+/K+ ATPase activation.
Dickerson MT, Dadi PK, Zaborska KE, Nakhe AY, Schaub CM, Dobson JR, Wright NM, Lynch JC, Scott CF, Robinson LD, Jacobson DA.
Dickerson MT, et al. Among authors: schaub cm.
Nat Commun. 2022 Oct 29;13(1):6461. doi: 10.1038/s41467-022-34166-z.
Nat Commun. 2022.
PMID: 36309517
Free PMC article.
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