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Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions.
Levey DF, Stein MB, Wendt FR, Pathak GA, Zhou H, Aslan M, Quaden R, Harrington KM, Nuñez YZ, Overstreet C, Radhakrishnan K, Sanacora G, McIntosh AM, Shi J, Shringarpure SS; 23andMe Research Team; Million Veteran Program; Concato J, Polimanti R, Gelernter J. Levey DF, et al. Among authors: sanacora g. Nat Neurosci. 2021 Jul;24(7):954-963. doi: 10.1038/s41593-021-00860-2. Epub 2021 May 27. Nat Neurosci. 2021. PMID: 34045744 Free PMC article.
Association of polymorphisms in HCN4 with mood disorders and obsessive compulsive disorder.
Kelmendi B, Holsbach-Beltrame M, McIntosh AM, Hilt L, George ED, Kitchen RR, Carlyle BC, Pittenger C, Coric V, Nolen-Hoeksema S, Sanacora G, Simen AA. Kelmendi B, et al. Among authors: sanacora g. Neurosci Lett. 2011 Jun 8;496(3):195-9. doi: 10.1016/j.neulet.2011.04.026. Epub 2011 Apr 20. Neurosci Lett. 2011. PMID: 21529705 Free PMC article.
Lower synaptic density is associated with depression severity and network alterations.
Holmes SE, Scheinost D, Finnema SJ, Naganawa M, Davis MT, DellaGioia N, Nabulsi N, Matuskey D, Angarita GA, Pietrzak RH, Duman RS, Sanacora G, Krystal JH, Carson RE, Esterlis I. Holmes SE, et al. Among authors: sanacora g. Nat Commun. 2019 Apr 4;10(1):1529. doi: 10.1038/s41467-019-09562-7. Nat Commun. 2019. PMID: 30948709 Free PMC article.
Major depression: emerging therapeutics.
Sen S, Sanacora G. Sen S, et al. Among authors: sanacora g. Mt Sinai J Med. 2008 May-Jun;75(3):204-25. doi: 10.1002/msj.20043. Mt Sinai J Med. 2008. PMID: 18704976 Review.
KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS.
Abdallah CG, Adams TG, Kelmendi B, Esterlis I, Sanacora G, Krystal JH. Abdallah CG, et al. Among authors: sanacora g. Depress Anxiety. 2016 Aug;33(8):689-97. doi: 10.1002/da.22501. Epub 2016 Apr 6. Depress Anxiety. 2016. PMID: 27062302 Free PMC article. Review.
189 results