Saldivar JC - Search Results

1

Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-deficient cancer models.

Mehibel M, Xu Y, Li CG, Moon EJ, Thakkar KN, Diep AN, Kim RK, Bloomstein JD, Xiao Y, Bacal J, Saldivar JC, Le QT, Cimprich KA, Rankin EB, Giaccia AJ. Mehibel M, et al. Among authors: saldivar jc. J Clin Invest. 2021 Jun 1;131(11):e146256. doi: 10.1172/JCI146256. J Clin Invest. 2021. PMID: 34060485 Free PMC article.

2

The essential kinase ATR: ensuring faithful duplication of a challenging genome.

Saldivar JC, Cortez D, Cimprich KA. Saldivar JC, et al. Nat Rev Mol Cell Biol. 2017 Oct;18(10):622-636. doi: 10.1038/nrm.2017.67. Epub 2017 Aug 16. Nat Rev Mol Cell Biol. 2017. PMID: 28811666 Free PMC article. Review.

3

A new mitotic activity comes into focus.

Saldivar JC, Cimprich KA. Saldivar JC, et al. Science. 2018 Jan 5;359(6371):30-31. doi: 10.1126/science.aar4799. Science. 2018. PMID: 29302000 No abstract available.

4

DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome.

Slaats GG, Saldivar JC, Bacal J, Zeman MK, Kile AC, Hynes AM, Srivastava S, Nazmutdinova J, den Ouden K, Zagers MS, Foletto V, Verhaar MC, Miles C, Sayer JA, Cimprich KA, Giles RH. Slaats GG, et al. Among authors: saldivar jc. J Clin Invest. 2015 Sep;125(9):3657-66. doi: 10.1172/JCI80657. Epub 2015 Aug 24. J Clin Invest. 2015. PMID: 26301811 Free PMC article.

5

Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses.

Hamperl S, Bocek MJ, Saldivar JC, Swigut T, Cimprich KA. Hamperl S, et al. Among authors: saldivar jc. Cell. 2017 Aug 10;170(4):774-786.e19. doi: 10.1016/j.cell.2017.07.043. Cell. 2017. PMID: 28802045 Free PMC article.

6

An intrinsic S/G₂ checkpoint enforced by ATR.

Saldivar JC, Hamperl S, Bocek MJ, Chung M, Bass TE, Cisneros-Soberanis F, Samejima K, Xie L, Paulson JR, Earnshaw WC, Cortez D, Meyer T, Cimprich KA. Saldivar JC, et al. Science. 2018 Aug 24;361(6404):806-810. doi: 10.1126/science.aap9346. Science. 2018. PMID: 30139873 Free PMC article.

7

Publisher correction: The essential kinase ATR: ensuring faithful duplication of a challenging genome.

Saldivar JC, Cortez D, Cimprich KA. Saldivar JC, et al. Nat Rev Mol Cell Biol. 2017 Dec;18(12):783. doi: 10.1038/nrm.2017.116. Epub 2017 Nov 8. Nat Rev Mol Cell Biol. 2017. PMID: 29115300 No abstract available.

8

Mechanisms shaping the mutational landscape of the FRA3B/FHIT-deficient cancer genome.

Saldivar JC, Park D. Saldivar JC, et al. Genes Chromosomes Cancer. 2019 May;58(5):317-323. doi: 10.1002/gcc.22684. Epub 2018 Nov 18. Genes Chromosomes Cancer. 2019. PMID: 30242938 Review.

9

Response of subtype-specific human breast cancer-derived cells to poly(ADP-ribose) polymerase and checkpoint kinase 1 inhibition.

Shibata H, Miuma S, Saldivar JC, Huebner K. Shibata H, et al. Among authors: saldivar jc. Cancer Sci. 2011 Oct;102(10):1882-8. doi: 10.1111/j.1349-7006.2011.02016.x. Epub 2011 Jul 21. Cancer Sci. 2011. PMID: 21707865 Free PMC article.

10

FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis.

Waters CE, Saldivar JC, Amin ZA, Schrock MS, Huebner K. Waters CE, et al. Among authors: saldivar jc. Oncotarget. 2015 Feb 20;6(5):3409-19. doi: 10.18632/oncotarget.2636. Oncotarget. 2015. PMID: 25401976 Free PMC article.

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