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Brain-penetrant LSD1 inhibitors can block memory consolidation.
Neelamegam R, Ricq EL, Malvaez M, Patnaik D, Norton S, Carlin SM, Hill IT, Wood MA, Haggarty SJ, Hooker JM. Neelamegam R, et al. Among authors: haggarty sj. ACS Chem Neurosci. 2012 Feb 15;3(2):120-128. doi: 10.1021/cn200104y. Epub 2011 Oct 18. ACS Chem Neurosci. 2012. PMID: 22754608 Free PMC article.
Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects.
Wagner FF, Bishop JA, Gale JP, Shi X, Walk M, Ketterman J, Patnaik D, Barker D, Walpita D, Campbell AJ, Nguyen S, Lewis M, Ross L, Weïwer M, An WF, Germain AR, Nag PP, Metkar S, Kaya T, Dandapani S, Olson DE, Barbe AL, Lazzaro F, Sacher JR, Cheah JH, Fei D, Perez J, Munoz B, Palmer M, Stegmaier K, Schreiber SL, Scolnick E, Zhang YL, Haggarty SJ, Holson EB, Pan JQ. Wagner FF, et al. Among authors: haggarty sj. ACS Chem Biol. 2016 Jul 15;11(7):1952-63. doi: 10.1021/acschembio.6b00306. Epub 2016 May 13. ACS Chem Biol. 2016. PMID: 27128528
Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability.
Silva MC, Cheng C, Mair W, Almeida S, Fong H, Biswas MHU, Zhang Z, Huang Y, Temple S, Coppola G, Geschwind DH, Karydas A, Miller BL, Kosik KS, Gao FB, Steen JA, Haggarty SJ. Silva MC, et al. Among authors: haggarty sj. Stem Cell Reports. 2016 Sep 13;7(3):325-340. doi: 10.1016/j.stemcr.2016.08.001. Epub 2016 Sep 1. Stem Cell Reports. 2016. PMID: 27594585 Free PMC article.
Classics in Chemical Neuroscience: Haloperidol.
Tyler MW, Zaldivar-Diez J, Haggarty SJ. Tyler MW, et al. Among authors: haggarty sj. ACS Chem Neurosci. 2017 Mar 15;8(3):444-453. doi: 10.1021/acschemneuro.7b00018. Epub 2017 Feb 15. ACS Chem Neurosci. 2017. PMID: 28170220
Development of [18F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging.
Hu K, Patnaik D, Collier TL, Lee KN, Gao H, Swoyer MR, Rotstein BH, Krishnan HS, Liang SH, Wang J, Yan Z, Hooker JM, Vasdev N, Haggarty SJ, Ngai MY. Hu K, et al. Among authors: haggarty sj. ACS Med Chem Lett. 2017 Feb 2;8(3):287-292. doi: 10.1021/acsmedchemlett.6b00405. eCollection 2017 Mar 9. ACS Med Chem Lett. 2017. PMID: 28337318 Free PMC article.
Classics in Chemical Neuroscience: Ketamine.
Tyler MW, Yourish HB, Ionescu DF, Haggarty SJ. Tyler MW, et al. Among authors: haggarty sj. ACS Chem Neurosci. 2017 Jun 21;8(6):1122-1134. doi: 10.1021/acschemneuro.7b00074. Epub 2017 Apr 21. ACS Chem Neurosci. 2017. PMID: 28418641 Review.
167 results