Hoffman G - Search Results

1

IL10RB as a key regulator of COVID-19 host susceptibility and severity.

Voloudakis G, Hoffman G, Venkatesh S, Lee KM, Dobrindt K, Vicari JM, Zhang W, Beckmann ND, Jiang S, Hoagland D, Bian J, Gao L, Corvelo A, Cho K, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative; Brennand KJ, Lynch JA, Fullard JF, Roussos P. Voloudakis G, et al. Among authors: hoffman g. medRxiv [Preprint]. 2021 Jun 2:2021.05.31.21254851. doi: 10.1101/2021.05.31.21254851. medRxiv. 2021. PMID: 34100031 Free PMC article. Updated. Preprint.

2

lrgpr: interactive linear mixed model analysis of genome-wide association studies with composite hypothesis testing and regression diagnostics in R.

Hoffman GE, Mezey JG, Schadt EE. Hoffman GE, et al. Bioinformatics. 2014 Nov 1;30(21):3134-5. doi: 10.1093/bioinformatics/btu435. Epub 2014 Jul 16. Bioinformatics. 2014. PMID: 25035399 Free PMC article.

3

Improved integrative framework combining association data with gene expression features to prioritize Crohn's disease genes.

Ning K, Gettler K, Zhang W, Ng SM, Bowen BM, Hyams J, Stephens MC, Kugathasan S, Denson LA, Schadt EE, Hoffman GE, Cho JH. Ning K, et al. Hum Mol Genet. 2015 Jul 15;24(14):4147-57. doi: 10.1093/hmg/ddv142. Epub 2015 May 1. Hum Mol Genet. 2015. PMID: 25935003 Free PMC article.

4

Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks.

Glicksberg BS, Li L, Badgeley MA, Shameer K, Kosoy R, Beckmann ND, Pho N, Hakenberg J, Ma M, Ayers KL, Hoffman GE, Dan Li S, Schadt EE, Patel CJ, Chen R, Dudley JT. Glicksberg BS, et al. Bioinformatics. 2016 Jun 15;32(12):i101-i110. doi: 10.1093/bioinformatics/btw282. Bioinformatics. 2016. PMID: 27307606 Free PMC article.

5

variancePartition: interpreting drivers of variation in complex gene expression studies.

Hoffman GE, Schadt EE. Hoffman GE, et al. BMC Bioinformatics. 2016 Nov 25;17(1):483. doi: 10.1186/s12859-016-1323-z. BMC Bioinformatics. 2016. PMID: 27884101 Free PMC article.

6

Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity.

Carcamo-Orive I, Hoffman GE, Cundiff P, Beckmann ND, D'Souza SL, Knowles JW, Patel A, Papatsenko D, Abbasi F, Reaven GM, Whalen S, Lee P, Shahbazi M, Henrion MYR, Zhu K, Wang S, Roussos P, Schadt EE, Pandey G, Chang R, Quertermous T, Lemischka I. Carcamo-Orive I, et al. Among authors: hoffman ge. Cell Stem Cell. 2017 Apr 6;20(4):518-532.e9. doi: 10.1016/j.stem.2016.11.005. Epub 2016 Dec 22. Cell Stem Cell. 2017. PMID: 28017796 Free PMC article.

7

Integrative transcriptomic analysis reveals key drivers of acute peanut allergic reactions.

Watson CT, Cohain AT, Griffin RS, Chun Y, Grishin A, Hacyznska H, Hoffman GE, Beckmann ND, Shah H, Dawson P, Henning A, Wood R, Burks AW, Jones SM, Leung DYM, Sicherer S, Sampson HA, Sharp AJ, Schadt EE, Bunyavanich S. Watson CT, et al. Among authors: hoffman ge. Nat Commun. 2017 Dec 5;8(1):1943. doi: 10.1038/s41467-017-02188-7. Nat Commun. 2017. PMID: 29203772 Free PMC article.

8

Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains.

Hoffman GE, Hartley BJ, Flaherty E, Ladran I, Gochman P, Ruderfer DM, Stahl EA, Rapoport J, Sklar P, Brennand KJ. Hoffman GE, et al. Nat Commun. 2017 Dec 20;8(1):2225. doi: 10.1038/s41467-017-02330-5. Nat Commun. 2017. PMID: 29263384 Free PMC article.

9

Mapping regulatory variants in hiPSC models.

Hoffman GE, Brennand KJ. Hoffman GE, et al. Nat Genet. 2018 Jan;50(1):1-2. doi: 10.1038/s41588-017-0017-4. Nat Genet. 2018. PMID: 29273803 No abstract available.

10

New considerations for hiPSC-based models of neuropsychiatric disorders.

Hoffman GE, Schrode N, Flaherty E, Brennand KJ. Hoffman GE, et al. Mol Psychiatry. 2019 Jan;24(1):49-66. doi: 10.1038/s41380-018-0029-1. Epub 2018 Feb 26. Mol Psychiatry. 2019. PMID: 29483625 Free PMC article. Review.

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