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Hexylether derivative of pyropheophorbide-a (HPPH) on conjugating with 3gadolinium(III) aminobenzyldiethylenetriaminepentaacetic acid shows potential for in vivo tumor imaging (MR, Fluorescence) and photodynamic therapy.
Spernyak JA, White WH 3rd, Ethirajan M, Patel NJ, Goswami L, Chen Y, Turowski S, Missert JR, Batt C, Mazurchuk R, Pandey RK. Spernyak JA, et al. Bioconjug Chem. 2010 May 19;21(5):828-35. doi: 10.1021/bc9005317. Bioconjug Chem. 2010. PMID: 20387862 Free PMC article.
Iron(II) PARACEST MRI contrast agents.
Dorazio SJ, Tsitovich PB, Siters KE, Spernyak JA, Morrow JR. Dorazio SJ, et al. Among authors: spernyak ja. J Am Chem Soc. 2011 Sep 14;133(36):14154-6. doi: 10.1021/ja204297z. Epub 2011 Aug 18. J Am Chem Soc. 2011. PMID: 21838276 Free PMC article.
Mechanisms of tumor vascular priming by a nanoparticulate doxorubicin formulation.
Roy Chaudhuri T, Arnold RD, Yang J, Turowski SG, Qu Y, Spernyak JA, Mazurchuk R, Mager DE, Straubinger RM. Roy Chaudhuri T, et al. Among authors: spernyak ja. Pharm Res. 2012 Dec;29(12):3312-24. doi: 10.1007/s11095-012-0823-4. Epub 2012 Jul 14. Pharm Res. 2012. PMID: 22798260 Free PMC article.
The NiCEST approach: nickel(II) paraCEST MRI contrast agents.
Olatunde AO, Dorazio SJ, Spernyak JA, Morrow JR. Olatunde AO, et al. Among authors: spernyak ja. J Am Chem Soc. 2012 Nov 14;134(45):18503-5. doi: 10.1021/ja307909x. Epub 2012 Nov 2. J Am Chem Soc. 2012. PMID: 23102112
CoCEST: cobalt(II) amide-appended paraCEST MRI contrast agents.
Dorazio SJ, Olatunde AO, Spernyak JA, Morrow JR. Dorazio SJ, et al. Among authors: spernyak ja. Chem Commun (Camb). 2013 Nov 4;49(85):10025-7. doi: 10.1039/c3cc45000g. Chem Commun (Camb). 2013. PMID: 24045271 Free PMC article.
60 results