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Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors.
Ojo KK, Pfander C, Mueller NR, Burstroem C, Larson ET, Bryan CM, Fox AM, Reid MC, Johnson SM, Murphy RC, Kennedy M, Mann H, Leibly DJ, Hewitt SN, Verlinde CL, Kappe S, Merritt EA, Maly DJ, Billker O, Van Voorhis WC. Ojo KK, et al. Among authors: reid mc. J Clin Invest. 2012 Jun;122(6):2301-5. doi: 10.1172/JCI61822. Epub 2012 May 8. J Clin Invest. 2012. PMID: 22565309 Free PMC article.
Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes.
Vidadala RS, Ojo KK, Johnson SM, Zhang Z, Leonard SE, Mitra A, Choi R, Reid MC, Keyloun KR, Fox AM, Kennedy M, Silver-Brace T, Hume JC, Kappe S, Verlinde CL, Fan E, Merritt EA, Van Voorhis WC, Maly DJ. Vidadala RS, et al. Among authors: reid mc. Eur J Med Chem. 2014 Mar 3;74:562-73. doi: 10.1016/j.ejmech.2013.12.048. Epub 2014 Jan 11. Eur J Med Chem. 2014. PMID: 24531197 Free PMC article.
A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation.
Ojo KK, Eastman RT, Vidadala R, Zhang Z, Rivas KL, Choi R, Lutz JD, Reid MC, Fox AM, Hulverson MA, Kennedy M, Isoherranen N, Kim LM, Comess KM, Kempf DJ, Verlinde CL, Su XZ, Kappe SH, Maly DJ, Fan E, Van Voorhis WC. Ojo KK, et al. Among authors: reid mc. J Infect Dis. 2014 Jan 15;209(2):275-84. doi: 10.1093/infdis/jit522. Epub 2013 Oct 10. J Infect Dis. 2014. PMID: 24123773 Free PMC article.
316 results