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Obesity accelerates hair thinning by stem cell-centric converging mechanisms.
Morinaga H, Mohri Y, Grachtchouk M, Asakawa K, Matsumura H, Oshima M, Takayama N, Kato T, Nishimori Y, Sorimachi Y, Takubo K, Suganami T, Iwama A, Iwakura Y, Dlugosz AA, Nishimura EK. Morinaga H, et al. Among authors: takubo k. Nature. 2021 Jul;595(7866):266-271. doi: 10.1038/s41586-021-03624-x. Epub 2021 Jun 23. Nature. 2021. PMID: 34163066 Free PMC article.
Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2.
Ueda T, Nagamachi A, Takubo K, Yamasaki N, Matsui H, Kanai A, Nakata Y, Ikeda K, Konuma T, Oda H, Wolff L, Honda Z, Wu X, Helin K, Iwama A, Suda T, Inaba T, Honda H. Ueda T, et al. Among authors: takubo k. Blood. 2015 May 28;125(22):3437-46. doi: 10.1182/blood-2014-03-562694. Epub 2015 Apr 14. Blood. 2015. PMID: 25872778 Free PMC article.
Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes.
Koide S, Oshima M, Takubo K, Yamazaki S, Nitta E, Saraya A, Aoyama K, Kato Y, Miyagi S, Nakajima-Takagi Y, Chiba T, Matsui H, Arai F, Suzuki Y, Kimura H, Nakauchi H, Suda T, Shinkai Y, Iwama A. Koide S, et al. Among authors: takubo k. Blood. 2016 Aug 4;128(5):638-49. doi: 10.1182/blood-2016-01-694810. Epub 2016 Jun 14. Blood. 2016. PMID: 27301860 Free article.
p38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress.
Karigane D, Kobayashi H, Morikawa T, Ootomo Y, Sakai M, Nagamatsu G, Kubota Y, Goda N, Matsumoto M, Nishimura EK, Soga T, Otsu K, Suematsu M, Okamoto S, Suda T, Takubo K. Karigane D, et al. Among authors: takubo k. Cell Stem Cell. 2016 Aug 4;19(2):192-204. doi: 10.1016/j.stem.2016.05.013. Epub 2016 Jun 23. Cell Stem Cell. 2016. PMID: 27345838 Free article.
UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes.
Sera Y, Nakata Y, Ueda T, Yamasaki N, Koide S, Kobayashi H, Ikeda KI, Kobatake K, Iwasaki M, Oda H, Wolff L, Kanai A, Nagamachi A, Inaba T, Sotomaru Y, Ichinohe T, Koizumi M, Miyakawa Y, Honda ZI, Iwama A, Suda T, Takubo K, Honda H. Sera Y, et al. Among authors: takubo k. Blood. 2021 Feb 18;137(7):908-922. doi: 10.1182/blood.2019001044. Blood. 2021. PMID: 33174606 Free PMC article.
OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy.
Murakami K, Kurotaki D, Kawase W, Soma S, Fukuchi Y, Kunimoto H, Yoshimi R, Koide S, Oshima M, Hishiki T, Hayakawa N, Matsuura T, Oda M, Yanagisawa K, Kobayashi H, Haraguchi M, Atobe Y, Funakoshi K, Iwama A, Takubo K, Okamoto S, Tamura T, Nakajima H. Murakami K, et al. Among authors: takubo k. Cell Rep. 2021 Jan 5;34(1):108579. doi: 10.1016/j.celrep.2020.108579. Cell Rep. 2021. PMID: 33406421 Free article.
432 results