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Targeting Glycolysis in Macrophages Confers Protection Against Pancreatic Ductal Adenocarcinoma.
Penny HL, Sieow JL, Gun SY, Lau MC, Lee B, Tan J, Phua C, Toh F, Nga Y, Yeap WH, Janela B, Kumar D, Chen H, Yeong J, Kenkel JA, Pang A, Lim D, Toh HC, Hon TLK, Johnson CI, Khameneh HJ, Mortellaro A, Engleman EG, Rotzschke O, Ginhoux F, Abastado JP, Chen J, Wong SC. Penny HL, et al. Among authors: engleman eg. Int J Mol Sci. 2021 Jun 14;22(12):6350. doi: 10.3390/ijms22126350. Int J Mol Sci. 2021. PMID: 34198548 Free PMC article.
B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies.
Winer DA, Winer S, Shen L, Wadia PP, Yantha J, Paltser G, Tsui H, Wu P, Davidson MG, Alonso MN, Leong HX, Glassford A, Caimol M, Kenkel JA, Tedder TF, McLaughlin T, Miklos DB, Dosch HM, Engleman EG. Winer DA, et al. Among authors: engleman eg. Nat Med. 2011 May;17(5):610-7. doi: 10.1038/nm.2353. Epub 2011 Apr 17. Nat Med. 2011. PMID: 21499269 Free PMC article.
Th17 cells induce Th1-polarizing monocyte-derived dendritic cells.
Davidson MG, Alonso MN, Yuan R, Axtell RC, Kenkel JA, Suhoski MM, González JC, Steinman L, Engleman EG. Davidson MG, et al. Among authors: engleman eg. J Immunol. 2013 Aug 1;191(3):1175-87. doi: 10.4049/jimmunol.1203201. Epub 2013 Jun 21. J Immunol. 2013. PMID: 23794631 Free PMC article.
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
Carmi Y, Spitzer MH, Linde IL, Burt BM, Prestwood TR, Perlman N, Davidson MG, Kenkel JA, Segal E, Pusapati GV, Bhattacharya N, Engleman EG. Carmi Y, et al. Among authors: engleman eg. Nature. 2015 May 7;521(7550):99-104. doi: 10.1038/nature14424. Epub 2015 Apr 29. Nature. 2015. PMID: 25924063 Free PMC article.
Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance.
Revelo XS, Ghazarian M, Chng MH, Luck H, Kim JH, Zeng K, Shi SY, Tsai S, Lei H, Kenkel J, Liu CL, Tangsombatvisit S, Tsui H, Sima C, Xiao C, Shen L, Li X, Jin T, Lewis GF, Woo M, Utz PJ, Glogauer M, Engleman E, Winer S, Winer DA. Revelo XS, et al. Cell Rep. 2016 Jul 19;16(3):717-30. doi: 10.1016/j.celrep.2016.06.024. Epub 2016 Jun 30. Cell Rep. 2016. PMID: 27373163 Free PMC article.
Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8(+) T Cell-Mediated Immunity in Colorectal Cancer.
Bhattacharya N, Yuan R, Prestwood TR, Penny HL, DiMaio MA, Reticker-Flynn NE, Krois CR, Kenkel JA, Pham TD, Carmi Y, Tolentino L, Choi O, Hulett R, Wang J, Winer DA, Napoli JL, Engleman EG. Bhattacharya N, et al. Among authors: engleman eg. Immunity. 2016 Sep 20;45(3):641-655. doi: 10.1016/j.immuni.2016.08.008. Epub 2016 Aug 30. Immunity. 2016. PMID: 27590114 Free PMC article.
Restoring Retinoic Acid Attenuates Intestinal Inflammation and Tumorigenesis in APCMin/+ Mice.
Penny HL, Prestwood TR, Bhattacharya N, Sun F, Kenkel JA, Davidson MG, Shen L, Zuniga LA, Seeley ES, Pai R, Choi O, Tolentino L, Wang J, Napoli JL, Engleman EG. Penny HL, et al. Among authors: engleman eg. Cancer Immunol Res. 2016 Nov;4(11):917-926. doi: 10.1158/2326-6066.CIR-15-0038. Epub 2016 Sep 16. Cancer Immunol Res. 2016. PMID: 27638841 Free PMC article.
309 results