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Targeting Glycolysis in Macrophages Confers Protection Against Pancreatic Ductal Adenocarcinoma.
Penny HL, Sieow JL, Gun SY, Lau MC, Lee B, Tan J, Phua C, Toh F, Nga Y, Yeap WH, Janela B, Kumar D, Chen H, Yeong J, Kenkel JA, Pang A, Lim D, Toh HC, Hon TLK, Johnson CI, Khameneh HJ, Mortellaro A, Engleman EG, Rotzschke O, Ginhoux F, Abastado JP, Chen J, Wong SC. Penny HL, et al. Among authors: rotzschke o. Int J Mol Sci. 2021 Jun 14;22(12):6350. doi: 10.3390/ijms22126350. Int J Mol Sci. 2021. PMID: 34198548 Free PMC article.
Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma.
Penny HL, Sieow JL, Adriani G, Yeap WH, See Chi Ee P, San Luis B, Lee B, Lee T, Mak SY, Ho YS, Lam KP, Ong CK, Huang RY, Ginhoux F, Rotzschke O, Kamm RD, Wong SC. Penny HL, et al. Among authors: rotzschke o. Oncoimmunology. 2016 Jun 21;5(8):e1191731. doi: 10.1080/2162402X.2016.1191731. eCollection 2016 Aug. Oncoimmunology. 2016. PMID: 27622062 Free PMC article.
Genome-wide analysis of the genetic regulation of gene expression in human neutrophils.
Andiappan AK, Melchiotti R, Poh TY, Nah M, Puan KJ, Vigano E, Haase D, Yusof N, San Luis B, Lum J, Kumar D, Foo S, Zhuang L, Vasudev A, Irwanto A, Lee B, Nardin A, Liu H, Zhang F, Connolly J, Liu J, Mortellaro A, Wang Y, Poidinger M, Larbi A, Zolezzi F, Rotzschke O. Andiappan AK, et al. Among authors: rotzschke o. Nat Commun. 2015 Aug 10;6:7971. doi: 10.1038/ncomms8971. Nat Commun. 2015. PMID: 26259071 Free PMC article.
Systematic characterization of basophil anergy.
Puan KJ, Andiappan AK, Lee B, Kumar D, Lai TS, Yeo G, Bercin D, Starke M, Haase D, Lum J, Chew FT, Connolly J, Wong SC, Zolezzi F, Poidinger M, Wang Y, Rötzschke O. Puan KJ, et al. Among authors: rotzschke o. Allergy. 2017 Mar;72(3):373-384. doi: 10.1111/all.12952. Epub 2016 Aug 8. Allergy. 2017. PMID: 27271846
A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus.
Kumar D, Puan KJ, Andiappan AK, Lee B, Westerlaken GH, Haase D, Melchiotti R, Li Z, Yusof N, Lum J, Koh G, Foo S, Yeong J, Alves AC, Pekkanen J, Sun LD, Irwanto A, Fairfax BP, Naranbhai V, Common JE, Tang M, Chuang CK, Jarvelin MR, Knight JC, Zhang X, Chew FT, Prabhakar S, Jianjun L, Wang Y, Zolezzi F, Poidinger M, Lane EB, Meyaard L, Rötzschke O. Kumar D, et al. Among authors: rotzschke o. Genome Med. 2017 Feb 20;9(1):18. doi: 10.1186/s13073-017-0404-6. Genome Med. 2017. PMID: 28219444 Free PMC article.
Atopic dermatitis microbiomes stratify into ecologic dermotypes enabling microbial virulence and disease severity.
Tay ASL, Li C, Nandi T, Chng KR, Andiappan AK, Mettu VS, de Cevins C, Ravikrishnan A, Dutertre CA, Wong XFCC, Ng AHQ, Matta SA, Ginhoux F, Rötzschke O, Chew FT, Tang MBY, Yew YW, Nagarajan N, Common JEA. Tay ASL, et al. Among authors: rotzschke o. J Allergy Clin Immunol. 2021 Apr;147(4):1329-1340. doi: 10.1016/j.jaci.2020.09.031. Epub 2020 Oct 8. J Allergy Clin Immunol. 2021. PMID: 33039480
145 results