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Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication.
Loft A, Alfaro AJ, Schmidt SF, Pedersen FB, Terkelsen MK, Puglia M, Chow KK, Feuchtinger A, Troullinaki M, Maida A, Wolff G, Sakurai M, Berutti R, Ekim Üstünel B, Nawroth P, Ravnskjaer K, Diaz MB, Blagoev B, Herzig S. Loft A, et al. Cell Metab. 2021 Aug 3;33(8):1685-1700.e9. doi: 10.1016/j.cmet.2021.06.005. Epub 2021 Jul 7. Cell Metab. 2021. PMID: 34237252 Free article.
A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.
Loft A, Schmidt SF, Caratti G, Stifel U, Havelund J, Sekar R, Kwon Y, Sulaj A, Chow KK, Alfaro AJ, Schwarzmayr T, Rittig N, Svart M, Tsokanos FF, Maida A, Blutke A, Feuchtinger A, Møller N, Blüher M, Nawroth P, Szendrödi J, Færgeman NJ, Zeigerer A, Tuckermann J, Herzig S. Loft A, et al. Cell Metab. 2022 Mar 1;34(3):473-486.e9. doi: 10.1016/j.cmet.2022.01.004. Epub 2022 Feb 3. Cell Metab. 2022. PMID: 35120589 Free article.
Purification of GFP-tagged nuclei from frozen livers of INTACT mice for RNA- and ATAC-sequencing.
Loft A, Herzig S, Schmidt SF. Loft A, et al. STAR Protoc. 2021 Sep 8;2(3):100805. doi: 10.1016/j.xpro.2021.100805. eCollection 2021 Sep 17. STAR Protoc. 2021. PMID: 34527961 Free PMC article.
Here, we present an improved protocol for isolation of pure and high-quality GFP-labeled nuclei from frozen livers of INTACT mice, as well as protocols for downstream sequencing analyses. The adaptation to frozen tissue provides a pause point that allows sampling at multip …
Here, we present an improved protocol for isolation of pure and high-quality GFP-labeled nuclei from frozen livers of INTACT mice, as well a …
Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.
Seitz S, Kwon Y, Hartleben G, Jülg J, Sekar R, Krahmer N, Najafi B, Loft A, Gancheva S, Stemmer K, Feuchtinger A, Hrabe de Angelis M, Müller TD, Mann M, Blüher M, Roden M, Berriel Diaz M, Behrends C, Gilleron J, Herzig S, Zeigerer A. Seitz S, et al. Among authors: loft a. Nat Metab. 2019 Oct;1(10):1009-1026. doi: 10.1038/s42255-019-0124-x. Epub 2019 Oct 14. Nat Metab. 2019. PMID: 32694843
Modulating the Genomic Programming of Adipocytes.
Loft A, Schmidt SF, Mandrup S. Loft A, et al. Cold Spring Harb Symp Quant Biol. 2015;80:239-48. doi: 10.1101/sqb.2015.80.027516. Epub 2015 Oct 2. Cold Spring Harb Symp Quant Biol. 2015. PMID: 26432526 Review.
Cofactor squelching: Artifact or fact?
Schmidt SF, Larsen BD, Loft A, Mandrup S. Schmidt SF, et al. Among authors: loft a. Bioessays. 2016 Jul;38(7):618-26. doi: 10.1002/bies.201600034. Epub 2016 Jun 7. Bioessays. 2016. PMID: 27273739 Review.
405 results