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Mutation of the 5'-untranslated region stem-loop mRNA structure reduces type I collagen deposition and arterial stiffness in male obese mice.
Ramirez-Perez FI, Woodford ML, Morales-Quinones M, Grunewald ZI, Cabral-Amador FJ, Yoshida T, Brenner DA, Manrique-Acevedo C, Martinez-Lemus LA, Chandrasekar B, Padilla J. Ramirez-Perez FI, et al. Among authors: chandrasekar b. Am J Physiol Heart Circ Physiol. 2021 Aug 1;321(2):H435-H445. doi: 10.1152/ajpheart.00076.2021. Epub 2021 Jul 9. Am J Physiol Heart Circ Physiol. 2021. PMID: 34242094 Free PMC article.
Angiotensin II enhances AT1-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT1, Nox1, and interleukin-18.
Valente AJ, Yoshida T, Murthy SN, Sakamuri SS, Katsuyama M, Clark RA, Delafontaine P, Chandrasekar B. Valente AJ, et al. Among authors: chandrasekar b. Am J Physiol Heart Circ Physiol. 2012 Aug 1;303(3):H282-96. doi: 10.1152/ajpheart.00231.2012. Epub 2012 May 25. Am J Physiol Heart Circ Physiol. 2012. PMID: 22636674 Free PMC article.
CIKS (Act1 or TRAF3IP2) mediates high glucose-induced endothelial dysfunction.
Venkatesan B, Valente AJ, Das NA, Carpenter AJ, Yoshida T, Delafontaine JL, Siebenlist U, Chandrasekar B. Venkatesan B, et al. Among authors: chandrasekar b. Cell Signal. 2013 Jan;25(1):359-71. doi: 10.1016/j.cellsig.2012.10.009. Epub 2012 Oct 17. Cell Signal. 2013. PMID: 23085260 Free PMC article.
Cardiac-restricted Overexpression of TRAF3 Interacting Protein 2 (TRAF3IP2) Results in Spontaneous Development of Myocardial Hypertrophy, Fibrosis, and Dysfunction.
Yariswamy M, Yoshida T, Valente AJ, Kandikattu HK, Sakamuri SS, Siddesha JM, Sukhanov S, Saifudeen Z, Ma L, Siebenlist U, Gardner JD, Chandrasekar B. Yariswamy M, et al. Among authors: chandrasekar b. J Biol Chem. 2016 Sep 9;291(37):19425-36. doi: 10.1074/jbc.M116.724138. Epub 2016 Jul 27. J Biol Chem. 2016. PMID: 27466370 Free PMC article.
Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice.
Aroor AR, Habibi J, Kandikattu HK, Garro-Kacher M, Barron B, Chen D, Hayden MR, Whaley-Connell A, Bender SB, Klein T, Padilla J, Sowers JR, Chandrasekar B, DeMarco VG. Aroor AR, et al. Among authors: chandrasekar b. Cardiovasc Diabetol. 2017 May 5;16(1):61. doi: 10.1186/s12933-017-0544-4. Cardiovasc Diabetol. 2017. PMID: 28476142 Free PMC article.
TRAF3IP2 mediates high glucose-induced endothelin-1 production as well as endothelin-1-induced inflammation in endothelial cells.
Padilla J, Carpenter AJ, Das NA, Kandikattu HK, López-Ongil S, Martinez-Lemus LA, Siebenlist U, DeMarco VG, Chandrasekar B. Padilla J, et al. Among authors: chandrasekar b. Am J Physiol Heart Circ Physiol. 2018 Jan 1;314(1):H52-H64. doi: 10.1152/ajpheart.00478.2017. Epub 2017 Sep 29. Am J Physiol Heart Circ Physiol. 2018. PMID: 28971844 Free PMC article.
231 results