McClay JL - Search Results

1

Epigenetic regulation of drug metabolism in aging.

McClay JL. McClay JL. Aging (Albany NY). 2021 Jul 11;13(13):16898-16899. doi: 10.18632/aging.203312. Epub 2021 Jul 11. Aging (Albany NY). 2021. PMID: 34251355 Free PMC article. No abstract available.

2

DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver.

Kronfol MM, Jahr FM, Dozmorov MG, Phansalkar PS, Xie LY, Aberg KA, McRae M, Price ET, Slattum PW, Gerk PM, McClay JL. Kronfol MM, et al. Among authors: mcclay jl. Geroscience. 2020 Jun;42(3):819-832. doi: 10.1007/s11357-020-00181-5. Epub 2020 Mar 27. Geroscience. 2020. PMID: 32221779 Free PMC article.

3

Histone acetylation at the sulfotransferase 1a1 gene is associated with its hepatic expression in normal aging.

Kronfol MM, Abudahab S, Dozmorov MG, Jahr FM, Halquist MS, McRae M, Wijesinghe DS, Price ET, Slattum PW, McClay JL. Kronfol MM, et al. Among authors: mcclay jl. Pharmacogenet Genomics. 2021 Dec 1;31(9):207-214. doi: 10.1097/FPC.0000000000000443. Pharmacogenet Genomics. 2021. PMID: 34320608 Free PMC article.

4

A methylome-wide study of aging using massively parallel sequencing of the methyl-CpG-enriched genomic fraction from blood in over 700 subjects.

McClay JL, Aberg KA, Clark SL, Nerella S, Kumar G, Xie LY, Hudson AD, Harada A, Hultman CM, Magnusson PK, Sullivan PF, Van Den Oord EJ. McClay JL, et al. Hum Mol Genet. 2014 Mar 1;23(5):1175-85. doi: 10.1093/hmg/ddt511. Epub 2013 Oct 16. Hum Mol Genet. 2014. PMID: 24135035 Free PMC article.

5

The ANKS1B gene and its associated phenotypes: focus on CNS drug response.

Younis RM, Taylor RM, Beardsley PM, McClay JL. Younis RM, et al. Among authors: mcclay jl. Pharmacogenomics. 2019 Jun;20(9):669-684. doi: 10.2217/pgs-2019-0015. Pharmacogenomics. 2019. PMID: 31250731 Free PMC article. Review.

6

Epigenetic histone acetylation and Bdnf dysregulation in the hippocampus of rats exposed to repeated, low-dose diisopropylfluorophosphate.

Ribeiro ACR, Jahr FM, Hawkins E, Kronfol MM, Younis RM, McClay JL, Deshpande LS. Ribeiro ACR, et al. Among authors: mcclay jl. Life Sci. 2021 Sep 15;281:119765. doi: 10.1016/j.lfs.2021.119765. Epub 2021 Jun 26. Life Sci. 2021. PMID: 34186043

7

Epigenetics in drug disposition & drug therapy: symposium report of the 24^th North American meeting of the International Society for the Study of Xenobiotics (ISSX).

Maldonato BJ, Vergara AG, Yadav J, Glass SM, Paragas EM, Li D, Lazarus P, McClay JL, Ning B, Daly AK, Russell LE. Maldonato BJ, et al. Among authors: mcclay jl. Drug Metab Rev. 2022 Aug;54(3):318-330. doi: 10.1080/03602532.2022.2101662. Epub 2022 Aug 24. Drug Metab Rev. 2022. PMID: 35876105 Free PMC article. Review.

8

Epigenetic regulation of drug metabolism in aging: utilizing epigenetics to optimize geriatric pharmacotherapy.

Abudahab S, Slattum PW, Price ET, McClay JL. Abudahab S, et al. Among authors: mcclay jl. Pharmacogenomics. 2024 Jan;25(1):41-54. doi: 10.2217/pgs-2023-0199. Epub 2023 Dec 21. Pharmacogenomics. 2024. PMID: 38126340 Review.

9

Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model.

Abudahab S, Kronfol MM, Dozmorov MG, Campbell T, Jahr FM, Nguyen J, AlAzzeh O, Al Saeedy DY, Victor A, Lee S, Malay S, Lapato DM, Halquist MS, McRae M, Deshpande LS, Slattum PW, Price ET, McClay JL. Abudahab S, et al. Among authors: mcclay jl. Geroscience. 2024 Apr 1. doi: 10.1007/s11357-024-01137-9. Online ahead of print. Geroscience. 2024. PMID: 38558216

10

Testing two models describing how methylome-wide studies in blood are informative for psychiatric conditions.

Aberg KA, Xie LY, McClay JL, Nerella S, Vunck S, Snider S, Beardsley PM, van den Oord EJ. Aberg KA, et al. Among authors: mcclay jl. Epigenomics. 2013 Aug;5(4):367-77. doi: 10.2217/epi.13.36. Epigenomics. 2013. PMID: 23895651 Free PMC article.

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