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Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity.
Wu X, Shukla R, Alganem K, Zhang X, Eby HM, Devine EA, Depasquale E, Reigle J, Simmons M, Hahn MK, Au-Yeung C, Asgariroozbehani R, Hahn CG, Haroutunian V, Meller J, Meador-Woodruff J, McCullumsmith RE. Wu X, et al. Among authors: hahn cg. Mol Psychiatry. 2021 Dec;26(12):7699-7708. doi: 10.1038/s41380-021-01205-y. Epub 2021 Jul 16. Mol Psychiatry. 2021. PMID: 34272489 Free PMC article.
mGluR5 hypofunction is integral to glutamatergic dysregulation in schizophrenia.
Wang HY, MacDonald ML, Borgmann-Winter KE, Banerjee A, Sleiman P, Tom A, Khan A, Lee KC, Roussos P, Siegel SJ, Hemby SE, Bilker WB, Gur RE, Hahn CG. Wang HY, et al. Among authors: hahn cg. Mol Psychiatry. 2020 Apr;25(4):750-760. doi: 10.1038/s41380-018-0234-y. Epub 2018 Sep 13. Mol Psychiatry. 2020. PMID: 30214040 Free PMC article.
CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder.
Hoffman GE, Bendl J, Voloudakis G, Montgomery KS, Sloofman L, Wang YC, Shah HR, Hauberg ME, Johnson JS, Girdhar K, Song L, Fullard JF, Kramer R, Hahn CG, Gur R, Marenco S, Lipska BK, Lewis DA, Haroutunian V, Hemby S, Sullivan P, Akbarian S, Chess A, Buxbaum JD, Crawford GE, Domenici E, Devlin B, Sieberts SK, Peters MA, Roussos P. Hoffman GE, et al. Among authors: hahn cg. Sci Data. 2019 Sep 24;6(1):180. doi: 10.1038/s41597-019-0183-6. Sci Data. 2019. PMID: 31551426 Free PMC article.
Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains.
Girdhar K, Hoffman GE, Bendl J, Rahman S, Dong P, Liao W, Hauberg ME, Sloofman L, Brown L, Devillers O, Kassim BS, Wiseman JR, Park R, Zharovsky E, Jacobov R, Flatow E, Kozlenkov A, Gilgenast T, Johnson JS, Couto L, Peters MA, Phillips-Cremins JE, Hahn CG, Gur RE, Tamminga CA, Lewis DA, Haroutunian V; PsychENCODE Consortium; Dracheva S, Lipska BK, Marenco S, Kundakovic M, Fullard JF, Jiang Y, Roussos P, Akbarian S. Girdhar K, et al. Among authors: hahn cg. Nat Neurosci. 2022 Apr;25(4):474-483. doi: 10.1038/s41593-022-01032-6. Epub 2022 Mar 24. Nat Neurosci. 2022. PMID: 35332326 Free PMC article.
107 results