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Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease.
Mulder K, Patel AA, Kong WT, Piot C, Halitzki E, Dunsmore G, Khalilnezhad S, Irac SE, Dubuisson A, Chevrier M, Zhang XM, Tam JKC, Lim TKH, Wong RMM, Pai R, Khalil AIS, Chow PKH, Wu SZ, Al-Eryani G, Roden D, Swarbrick A, Chan JKY, Albani S, Derosa L, Zitvogel L, Sharma A, Chen J, Silvin A, Bertoletti A, Blériot C, Dutertre CA, Ginhoux F. Mulder K, et al. Among authors: ginhoux f. Immunity. 2021 Aug 10;54(8):1883-1900.e5. doi: 10.1016/j.immuni.2021.07.007. Epub 2021 Jul 30. Immunity. 2021. PMID: 34331874 Free article.
Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells.
Haniffa M, Shin A, Bigley V, McGovern N, Teo P, See P, Wasan PS, Wang XN, Malinarich F, Malleret B, Larbi A, Tan P, Zhao H, Poidinger M, Pagan S, Cookson S, Dickinson R, Dimmick I, Jarrett RF, Renia L, Tam J, Song C, Connolly J, Chan JK, Gehring A, Bertoletti A, Collin M, Ginhoux F. Haniffa M, et al. Among authors: ginhoux f. Immunity. 2012 Jul 27;37(1):60-73. doi: 10.1016/j.immuni.2012.04.012. Epub 2012 Jul 12. Immunity. 2012. PMID: 22795876 Free PMC article.
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes.
Hashimoto D, Chow A, Noizat C, Teo P, Beasley MB, Leboeuf M, Becker CD, See P, Price J, Lucas D, Greter M, Mortha A, Boyer SW, Forsberg EC, Tanaka M, van Rooijen N, García-Sastre A, Stanley ER, Ginhoux F, Frenette PS, Merad M. Hashimoto D, et al. Among authors: ginhoux f. Immunity. 2013 Apr 18;38(4):792-804. doi: 10.1016/j.immuni.2013.04.004. Immunity. 2013. PMID: 23601688 Free PMC article.
IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses.
Schlitzer A, McGovern N, Teo P, Zelante T, Atarashi K, Low D, Ho AW, See P, Shin A, Wasan PS, Hoeffel G, Malleret B, Heiseke A, Chew S, Jardine L, Purvis HA, Hilkens CM, Tam J, Poidinger M, Stanley ER, Krug AB, Renia L, Sivasankar B, Ng LG, Collin M, Ricciardi-Castagnoli P, Honda K, Haniffa M, Ginhoux F. Schlitzer A, et al. Among authors: ginhoux f. Immunity. 2013 May 23;38(5):970-83. doi: 10.1016/j.immuni.2013.04.011. Immunity. 2013. PMID: 23706669 Free PMC article.
Human dermal CD14⁺ cells are a transient population of monocyte-derived macrophages.
McGovern N, Schlitzer A, Gunawan M, Jardine L, Shin A, Poyner E, Green K, Dickinson R, Wang XN, Low D, Best K, Covins S, Milne P, Pagan S, Aljefri K, Windebank M, Miranda-Saavedra D, Larbi A, Wasan PS, Duan K, Poidinger M, Bigley V, Ginhoux F, Collin M, Haniffa M. McGovern N, et al. Among authors: ginhoux f. Immunity. 2014 Sep 18;41(3):465-477. doi: 10.1016/j.immuni.2014.08.006. Epub 2014 Sep 4. Immunity. 2014. PMID: 25200712 Free PMC article.
Aligning bona fide dendritic cell populations across species.
Dutertre CA, Wang LF, Ginhoux F. Dutertre CA, et al. Among authors: ginhoux f. Cell Immunol. 2014 Sep-Oct;291(1-2):3-10. doi: 10.1016/j.cellimm.2014.08.006. Epub 2014 Sep 4. Cell Immunol. 2014. PMID: 25262488 Review.
C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages.
Hoeffel G, Chen J, Lavin Y, Low D, Almeida FF, See P, Beaudin AE, Lum J, Low I, Forsberg EC, Poidinger M, Zolezzi F, Larbi A, Ng LG, Chan JK, Greter M, Becher B, Samokhvalov IM, Merad M, Ginhoux F. Hoeffel G, et al. Among authors: ginhoux f. Immunity. 2015 Apr 21;42(4):665-78. doi: 10.1016/j.immuni.2015.03.011. Immunity. 2015. PMID: 25902481 Free PMC article.
361 results