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The CARB-X Portfolio of Nontraditional Antibacterial Products.
Duffy EM, Buurman ET, Chiang SL, Cohen NR, Uria-Nickelsen M, Alm RA. Duffy EM, et al. Among authors: alm ra. ACS Infect Dis. 2021 Aug 13;7(8):2043-2049. doi: 10.1021/acsinfecdis.1c00331. Epub 2021 Aug 4. ACS Infect Dis. 2021. PMID: 34346202
A novel pre-clinical antibacterial pipeline database.
Paulin S, Alm RA, Beyer P. Paulin S, et al. Among authors: alm ra. PLoS One. 2020 Jul 28;15(7):e0236604. doi: 10.1371/journal.pone.0236604. eCollection 2020. PLoS One. 2020. PMID: 32722726 Free PMC article.
Helicobacter pylori physiology predicted from genomic comparison of two strains.
Doig P, de Jonge BL, Alm RA, Brown ED, Uria-Nickelsen M, Noonan B, Mills SD, Tummino P, Carmel G, Guild BC, Moir DT, Vovis GF, Trust TJ. Doig P, et al. Among authors: alm ra. Microbiol Mol Biol Rev. 1999 Sep;63(3):675-707. doi: 10.1128/MMBR.63.3.675-707.1999. Microbiol Mol Biol Rev. 1999. PMID: 10477312 Free PMC article. Review.
Analysis of the Clinical Pipeline of Treatments for Drug-Resistant Bacterial Infections: Despite Progress, More Action Is Needed.
Butler MS, Gigante V, Sati H, Paulin S, Al-Sulaiman L, Rex JH, Fernandes P, Arias CA, Paul M, Thwaites GE, Czaplewski L, Alm RA, Lienhardt C, Spigelman M, Silver LL, Ohmagari N, Kozlov R, Harbarth S, Beyer P. Butler MS, et al. Among authors: alm ra. Antimicrob Agents Chemother. 2022 Mar 15;66(3):e0199121. doi: 10.1128/AAC.01991-21. Epub 2022 Jan 10. Antimicrob Agents Chemother. 2022. PMID: 35007139 Free PMC article. Review.
Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II: broad-spectrum antibacterial agents with reduced hERG activity.
Reck F, Alm R, Brassil P, Newman J, Dejonge B, Eyermann CJ, Breault G, Breen J, Comita-Prevoir J, Cronin M, Davis H, Ehmann D, Galullo V, Geng B, Grebe T, Morningstar M, Walker P, Hayter B, Fisher S. Reck F, et al. J Med Chem. 2011 Nov 24;54(22):7834-47. doi: 10.1021/jm2008826. Epub 2011 Oct 27. J Med Chem. 2011. PMID: 21999508
Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II with reduced pK(a): antibacterial agents with an improved safety profile.
Reck F, Alm RA, Brassil P, Newman JV, Ciaccio P, McNulty J, Barthlow H, Goteti K, Breen J, Comita-Prevoir J, Cronin M, Ehmann DE, Geng B, Godfrey AA, Fisher SL. Reck F, et al. Among authors: alm ra. J Med Chem. 2012 Aug 9;55(15):6916-33. doi: 10.1021/jm300690s. Epub 2012 Jul 20. J Med Chem. 2012. PMID: 22779424
84 results