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METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation.
Orellana EA, Liu Q, Yankova E, Pirouz M, De Braekeleer E, Zhang W, Lim J, Aspris D, Sendinc E, Garyfallos DA, Gu M, Ali R, Gutierrez A, Mikutis S, Bernardes GJL, Fischer ES, Bradley A, Vassiliou GS, Slack FJ, Tzelepis K, Gregory RI. Orellana EA, et al. Among authors: bernardes gjl. Mol Cell. 2021 Aug 19;81(16):3323-3338.e14. doi: 10.1016/j.molcel.2021.06.031. Epub 2021 Aug 4. Mol Cell. 2021. PMID: 34352207 Free PMC article.
Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules.
Mikutis S, Rebelo M, Yankova E, Gu M, Tang C, Coelho AR, Yang M, Hazemi ME, Pires de Miranda M, Eleftheriou M, Robertson M, Vassiliou GS, Adams DJ, Simas JP, Corzana F, Schneekloth JS Jr, Tzelepis K, Bernardes GJL. Mikutis S, et al. Among authors: bernardes gjl. ACS Cent Sci. 2023 Apr 26;9(5):892-904. doi: 10.1021/acscentsci.3c00015. eCollection 2023 May 24. ACS Cent Sci. 2023. PMID: 37252343 Free PMC article.
Controlled masking and targeted release of redox-cycling ortho-quinones via a C-C bond-cleaving 1,6-elimination.
Dunsmore L, Navo CD, Becher J, de Montes EG, Guerreiro A, Hoyt E, Brown L, Zelenay V, Mikutis S, Cooper J, Barbieri I, Lawrinowitz S, Siouve E, Martin E, Ruivo PR, Rodrigues T, da Cruz FP, Werz O, Vassiliou G, Ravn P, Jiménez-Osés G, Bernardes GJL. Dunsmore L, et al. Among authors: bernardes gjl. Nat Chem. 2022 Jul;14(7):754-765. doi: 10.1038/s41557-022-00964-7. Epub 2022 Jun 27. Nat Chem. 2022. PMID: 35764792 Free PMC article.
Protein-Protein Conjugates: Tyrosine Delivers.
Geeson MB, Bernardes GJL. Geeson MB, et al. Among authors: bernardes gjl. ACS Cent Sci. 2020 Sep 23;6(9):1473-1475. doi: 10.1021/acscentsci.0c01008. Epub 2020 Aug 25. ACS Cent Sci. 2020. PMID: 32999919 Free PMC article. No abstract available.
176 results