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An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity.
Xu Y, Carrascosa LC, Yeung YA, Chu ML, Yang W, Djuretic I, Pappas DC, Zeytounian J, Ge Z, de Ruiter V, Starbeck-Miller GR, Patterson J, Rigas D, Chen SH, Kraynov E, Boor PP, Noordam L, Doukas M, Tsao D, Ijzermans JN, Guo J, Grünhagen DJ, Erdmann J, Verheij J, van Royen ME, Doornebosch PG, Feldman R, Park T, Mahmoudi S, Dorywalska M, Ni I, Chin SM, Mistry T, Mosyak L, Lin L, Ching KA, Lindquist KC, Ji C, Londono LM, Kuang B, Rickert R, Kwekkeboom J, Sprengers D, Huang TH, Chaparro-Riggers J. Xu Y, et al. Among authors: doornebosch pg. Cancer Immunol Res. 2021 Oct;9(10):1141-1157. doi: 10.1158/2326-6066.CIR-21-0058. Epub 2021 Aug 10. Cancer Immunol Res. 2021. PMID: 34376502
Adjuvant hepatic arterial infusion pump chemotherapy and resection versus resection alone in patients with low-risk resectable colorectal liver metastases - the multicenter randomized controlled PUMP trial.
Buisman FE, Homs MYV, Grünhagen DJ, Filipe WF, Bennink RJ, Besselink MGH, Borel Rinkes IHM, Bruijnen RCG, Cercek A, D'Angelica MI, van Delden OM, Donswijk ML, van Doorn L, Doornebosch PG, Emmering J, Erdmann JI, IJzerman NS, Grootscholten C, Hagendoorn J, Kemeny NE, Kingham TP, Klompenhouwer EG, Kok NFM, Koolen S, Kuhlmann KFD, Kuiper MC, Lam MGE, Mathijssen RHJ, Moelker A, Oomen-de Hoop E, Punt CJA, Te Riele WW, Roodhart JML, Swijnenburg RJ, Prevoo W, Tanis PJ, Vermaas M, Versleijen MWJ, Veuger FP, Weterman MJ, Verhoef C, Groot Koerkamp B. Buisman FE, et al. Among authors: doornebosch pg. BMC Cancer. 2019 Apr 5;19(1):327. doi: 10.1186/s12885-019-5515-6. BMC Cancer. 2019. PMID: 30953467 Free PMC article.
FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells.
Campos Carrascosa L, van Beek AA, de Ruiter V, Doukas M, Wei J, Fisher TS, Ching K, Yang W, van Loon K, Boor PPC, Rakké YS, Noordam L, Doornebosch P, Grünhagen D, Verhoef K, Polak WG, IJzermans JNM, Ni I, Yeung YA, Salek-Ardakani S, Sprengers D, Kwekkeboom J. Campos Carrascosa L, et al. J Immunother Cancer. 2020 Sep;8(2):e000816. doi: 10.1136/jitc-2020-000816. J Immunother Cancer. 2020. PMID: 32900860 Free PMC article.
GITR Ligation Improves Anti-PD1-Mediated Restoration of Human MMR-Proficient Colorectal Carcinoma Tumor-Derived T Cells.
Rakké YS, Campos Carrascosa L, van Beek AA, de Ruiter V, van Gemerden RS, Doukas M, Doornebosch PG, Vermaas M, Ter Borg S, van der Harst E, Coene PPLO, Kliffen M, Grünhagen DJ, Verhoef C, IJzermans JNM, Kwekkeboom J, Sprengers D. Rakké YS, et al. Among authors: doornebosch pg. Cell Mol Gastroenterol Hepatol. 2023;15(1):77-97. doi: 10.1016/j.jcmgh.2022.09.007. Epub 2022 Sep 23. Cell Mol Gastroenterol Hepatol. 2023. PMID: 36155259 Free PMC article.
Short-term postoperative outcomes after liver resection in the elderly patient: a nationwide population-based study.
Elfrink AKE, Kok NFM, den Dulk M, Buis CI, Kazemier G, Ijzermans JNM, Lam HD, Hagendoorn J, van den Boezem PB, Ayez N, Zonderhuis BM, Lips DJ, Leclercq WKG, Kuhlmann KFD, Marsman HA, Verhoef C, Patijn GA, Grünhagen DJ, Klaase JM; Collaborators; Dutch Hepato Biliary Audit Group. Elfrink AKE, et al. HPB (Oxford). 2021 Oct;23(10):1506-1517. doi: 10.1016/j.hpb.2021.03.002. Epub 2021 Mar 19. HPB (Oxford). 2021. PMID: 33926842 Free article.
Systemic exposure of floxuridine after hepatic arterial infusion pump chemotherapy with floxuridine in patients with resected colorectal liver metastases.
IJzerman NS, Filipe WF, Bruijn P, Buisman FE, Doorn LV, Doornebosch PG, Holster JJ, Grootscholten C, Grünhagen DJ, van Bommel CPE, Homs MYV, Kok NFM, Verhoef C, Koerkamp BG, Kuhlmann KFD, Mathijssen RHJ, Koolen SLW. IJzerman NS, et al. Among authors: doornebosch pg. Biomed Pharmacother. 2023 Jun;162:114625. doi: 10.1016/j.biopha.2023.114625. Epub 2023 Apr 12. Biomed Pharmacother. 2023. PMID: 37058821 Free article.
B cell immune profiles in dysbiotic vermiform appendixes of pancreatic cancer patients.
Vietsch EE, Latifi D, Verheij M, van der Oost EWA, de Wilde RF, Haen R, van den Boom AL, Koerkamp BG, Doornebosch PG, van Verschuer VMT, Ooms AHAG, Mohammad F, Willemsen M, Aerts JGJV, Krog RT, de Miranda NFCC, van den Bosch TPP, Mueller YM, Katsikis PD, van Eijck CHJ. Vietsch EE, et al. Among authors: doornebosch pg. Front Immunol. 2023 Nov 10;14:1230306. doi: 10.3389/fimmu.2023.1230306. eCollection 2023. Front Immunol. 2023. PMID: 38022530 Free PMC article.
Progression and tumor heterogeneity analysis in early rectal cancer.
Lips EH, van Eijk R, de Graaf EJ, Doornebosch PG, de Miranda NF, Oosting J, Karsten T, Eilers PH, Tollenaar RA, van Wezel T, Morreau H. Lips EH, et al. Among authors: doornebosch pg. Clin Cancer Res. 2008 Feb 1;14(3):772-81. doi: 10.1158/1078-0432.CCR-07-2052. Clin Cancer Res. 2008. PMID: 18245538
95 results