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An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity.
Xu Y, Carrascosa LC, Yeung YA, Chu ML, Yang W, Djuretic I, Pappas DC, Zeytounian J, Ge Z, de Ruiter V, Starbeck-Miller GR, Patterson J, Rigas D, Chen SH, Kraynov E, Boor PP, Noordam L, Doukas M, Tsao D, Ijzermans JN, Guo J, Grünhagen DJ, Erdmann J, Verheij J, van Royen ME, Doornebosch PG, Feldman R, Park T, Mahmoudi S, Dorywalska M, Ni I, Chin SM, Mistry T, Mosyak L, Lin L, Ching KA, Lindquist KC, Ji C, Londono LM, Kuang B, Rickert R, Kwekkeboom J, Sprengers D, Huang TH, Chaparro-Riggers J. Xu Y, et al. Among authors: doukas m. Cancer Immunol Res. 2021 Oct;9(10):1141-1157. doi: 10.1158/2326-6066.CIR-21-0058. Epub 2021 Aug 10. Cancer Immunol Res. 2021. PMID: 34376502
Hepatocellular adenoma: when and how to treat? Update of current evidence.
Thomeer MG, Broker M, Verheij J, Doukas M, Terkivatan T, Bijdevaate D, De Man RA, Moelker A, IJzermans JN. Thomeer MG, et al. Among authors: doukas m. Therap Adv Gastroenterol. 2016 Nov;9(6):898-912. doi: 10.1177/1756283X16663882. Epub 2016 Sep 28. Therap Adv Gastroenterol. 2016. PMID: 27803743 Free PMC article. Review.
Response to Chen et al.
Klompenhouwer AJ, Alblas M, van Rosmalen BV, Haring MPD, Venema E, Doukas M, Thomeer MGJ, Takkenberg RB, Verheij J, de Meijer VE, van Gulik TM, Lingsma HF, de Man RA, Ijzermans JNM. Klompenhouwer AJ, et al. Among authors: doukas m. Am J Gastroenterol. 2020 Jan;115(1):147-148. doi: 10.14309/ajg.0000000000000488. Am J Gastroenterol. 2020. PMID: 31842143 No abstract available.
LGR5 marks targetable tumor-initiating cells in mouse liver cancer.
Cao W, Li M, Liu J, Zhang S, Noordam L, Verstegen MMA, Wang L, Ma B, Li S, Wang W, Bolkestein M, Doukas M, Chen K, Ma Z, Bruno M, Sprengers D, Kwekkeboom J, van der Laan LJW, Smits R, Peppelenbosch MP, Pan Q. Cao W, et al. Among authors: doukas m. Nat Commun. 2020 Apr 23;11(1):1961. doi: 10.1038/s41467-020-15846-0. Nat Commun. 2020. PMID: 32327656 Free PMC article.
TIGIT and PD1 Co-blockade Restores ex vivo Functions of Human Tumor-Infiltrating CD8+ T Cells in Hepatocellular Carcinoma.
Ge Z, Zhou G, Campos Carrascosa L, Gausvik E, Boor PPC, Noordam L, Doukas M, Polak WG, Terkivatan T, Pan Q, Takkenberg RB, Verheij J, Erdmann JI, IJzermans JNM, Peppelenbosch MP, Kraan J, Kwekkeboom J, Sprengers D. Ge Z, et al. Among authors: doukas m. Cell Mol Gastroenterol Hepatol. 2021;12(2):443-464. doi: 10.1016/j.jcmgh.2021.03.003. Epub 2021 Mar 27. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33781741 Free PMC article.
204 results