Mitchell J - Search Results

1

Cytoplasmic TDP-43 is involved in cell fate during stress recovery.

Lee YB, Scotter EL, Lee DY, Troakes C, Mitchell J, Rogelj B, Gallo JM, Shaw CE. Lee YB, et al. Among authors: mitchell j. Hum Mol Genet. 2021 Dec 27;31(2):166-175. doi: 10.1093/hmg/ddab227. Hum Mol Genet. 2021. PMID: 34378050 Free PMC article.

2

The X11/Mint family of adaptor proteins.

Rogelj B, Mitchell JC, Miller CC, McLoughlin DM. Rogelj B, et al. Among authors: mitchell jc. Brain Res Rev. 2006 Sep;52(2):305-15. doi: 10.1016/j.brainresrev.2006.04.005. Epub 2006 Jun 9. Brain Res Rev. 2006. PMID: 16764936 Review.

3

X11beta rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice.

Mitchell JC, Ariff BB, Yates DM, Lau KF, Perkinton MS, Rogelj B, Stephenson JD, Miller CC, McLoughlin DM. Mitchell JC, et al. Hum Mol Genet. 2009 Dec 1;18(23):4492-500. doi: 10.1093/hmg/ddp408. Epub 2009 Sep 10. Hum Mol Genet. 2009. PMID: 19744962 Free PMC article.

4

Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology.

Tudor EL, Galtrey CM, Perkinton MS, Lau KF, De Vos KJ, Mitchell JC, Ackerley S, Hortobágyi T, Vámos E, Leigh PN, Klasen C, McLoughlin DM, Shaw CE, Miller CC. Tudor EL, et al. Among authors: mitchell jc. Neuroscience. 2010 May 19;167(3):774-85. doi: 10.1016/j.neuroscience.2010.02.035. Epub 2010 Feb 24. Neuroscience. 2010. PMID: 20188146

5

Expression of the neuronal adaptor protein X11alpha protects against memory dysfunction in a transgenic mouse model of Alzheimer's disease.

Mitchell JC, Perkinton MS, Yates DM, Lau KF, Rogelj B, Miller CC, McLoughlin DM. Mitchell JC, et al. J Alzheimers Dis. 2010;20(1):31-6. doi: 10.3233/JAD-2009-1341. J Alzheimers Dis. 2010. PMID: 20378958 Free PMC article.

6

Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion.

Mitchell JC, McGoldrick P, Vance C, Hortobagyi T, Sreedharan J, Rogelj B, Tudor EL, Smith BN, Klasen C, Miller CC, Cooper JD, Greensmith L, Shaw CE. Mitchell JC, et al. Acta Neuropathol. 2013 Feb;125(2):273-88. doi: 10.1007/s00401-012-1043-z. Epub 2012 Sep 9. Acta Neuropathol. 2013. PMID: 22961620 Free PMC article.

7

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules.

Vance C, Scotter EL, Nishimura AL, Troakes C, Mitchell JC, Kathe C, Urwin H, Manser C, Miller CC, Hortobágyi T, Dragunow M, Rogelj B, Shaw CE. Vance C, et al. Hum Mol Genet. 2013 Jul 1;22(13):2676-88. doi: 10.1093/hmg/ddt117. Epub 2013 Mar 7. Hum Mol Genet. 2013. PMID: 23474818 Free PMC article.

8

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species.

Scotter EL, Vance C, Nishimura AL, Lee YB, Chen HJ, Urwin H, Sardone V, Mitchell JC, Rogelj B, Rubinsztein DC, Shaw CE. Scotter EL, et al. J Cell Sci. 2014 Mar 15;127(Pt 6):1263-78. doi: 10.1242/jcs.140087. Epub 2014 Jan 14. J Cell Sci. 2014. PMID: 24424030 Free PMC article.

9

ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43.

Stoica R, De Vos KJ, Paillusson S, Mueller S, Sancho RM, Lau KF, Vizcay-Barrena G, Lin WL, Xu YF, Lewis J, Dickson DW, Petrucelli L, Mitchell JC, Shaw CE, Miller CC. Stoica R, et al. Among authors: mitchell jc. Nat Commun. 2014 Jun 3;5:3996. doi: 10.1038/ncomms4996. Nat Commun. 2014. PMID: 24893131 Free PMC article.

10

Novel mutations support a role for Profilin 1 in the pathogenesis of ALS.

Smith BN, Vance C, Scotter EL, Troakes C, Wong CH, Topp S, Maekawa S, King A, Mitchell JC, Lund K, Al-Chalabi A, Ticozzi N, Silani V, Sapp P, Brown RH Jr, Landers JE, Al-Sarraj S, Shaw CE. Smith BN, et al. Neurobiol Aging. 2015 Mar;36(3):1602.e17-27. doi: 10.1016/j.neurobiolaging.2014.10.032. Epub 2014 Oct 31. Neurobiol Aging. 2015. PMID: 25499087 Free PMC article.

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