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A therapeutic cancer vaccine delivers antigens and adjuvants to lymphoid tissues using genetically modified T cells.
J Clin Invest. 2021 Aug 16;131(16):e144195. doi: 10.1172/JCI144195.
J Clin Invest. 2021.
PMID: 34396986
Free PMC article.
Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma.
Veatch JR, Lee SM, Fitzgibbon M, Chow IT, Jesernig B, Schmitt T, Kong YY, Kargl J, Houghton AM, Thompson JA, McIntosh M, Kwok WW, Riddell SR.
Veatch JR, et al. Among authors: jesernig b.
J Clin Invest. 2018 Apr 2;128(4):1563-1568. doi: 10.1172/JCI98689. Epub 2018 Mar 12.
J Clin Invest. 2018.
PMID: 29360643
Free PMC article.
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Mobilization of pre-existing polyclonal T cells specific to neoantigens but not self-antigens during treatment of a patient with melanoma with bempegaldesleukin and nivolumab.
Veatch JR, Singhi N, Jesernig B, Paulson KG, Zalevsky J, Iaccucci E, Tykodi SS, Riddell SR.
Veatch JR, et al. Among authors: jesernig b.
J Immunother Cancer. 2020 Dec;8(2):e001591. doi: 10.1136/jitc-2020-001591.
J Immunother Cancer. 2020.
PMID: 33298619
Free PMC article.
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Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function.
Veatch JR, Lee SM, Shasha C, Singhi N, Szeto JL, Moshiri AS, Kim TS, Smythe K, Kong P, Fitzgibbon M, Jesernig B, Bhatia S, Tykodi SS, Hall ET, Byrd DR, Thompson JA, Pillarisetty VG, Duhen T, McGarry Houghton A, Newell E, Gottardo R, Riddell SR.
Veatch JR, et al. Among authors: jesernig b.
Cancer Cell. 2022 Apr 11;40(4):393-409.e9. doi: 10.1016/j.ccell.2022.03.006.
Cancer Cell. 2022.
PMID: 35413271
Free PMC article.
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Endogenous CD4+ T Cells Recognize Neoantigens in Lung Cancer Patients, Including Recurrent Oncogenic KRAS and ERBB2 (Her2) Driver Mutations.
Veatch JR, Jesernig BL, Kargl J, Fitzgibbon M, Lee SM, Baik C, Martins R, Houghton AM, Riddell SR.
Veatch JR, et al. Among authors: jesernig bl.
Cancer Immunol Res. 2019 Jun;7(6):910-922. doi: 10.1158/2326-6066.CIR-18-0402. Epub 2019 May 1.
Cancer Immunol Res. 2019.
PMID: 31043415
Free PMC article.
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