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Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.
Rankin EB, Fuh KC, Castellini L, Viswanathan K, Finger EC, Diep AN, LaGory EL, Kariolis MS, Chan A, Lindgren D, Axelson H, Miao YR, Krieg AJ, Giaccia AJ. Rankin EB, et al. Among authors: fuh kc. Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13373-8. doi: 10.1073/pnas.1404848111. Epub 2014 Sep 3. Proc Natl Acad Sci U S A. 2014. PMID: 25187556 Free PMC article.
AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer.
Divine LM, Nguyen MR, Meller E, Desai RA, Arif B, Rankin EB, Bligard KH, Meyerson C, Hagemann IS, Massad M, Thaker PH, Hagemann AR, McCourt CK, Powell MA, Mutch DG, Fuh KC. Divine LM, et al. Among authors: fuh kc. Oncotarget. 2016 Nov 22;7(47):77291-77305. doi: 10.18632/oncotarget.12637. Oncotarget. 2016. PMID: 27764792 Free PMC article.
Therapeutic Inhibition of the Receptor Tyrosine Kinase AXL Improves Sensitivity to Platinum and Taxane in Ovarian Cancer.
Quinn JM, Greenwade MM, Palisoul ML, Opara G, Massad K, Guo L, Zhao P, Beck-Noia H, Hagemann IS, Hagemann AR, McCourt CK, Thaker PH, Powell MA, Mutch DG, Fuh KC. Quinn JM, et al. Among authors: fuh kc. Mol Cancer Ther. 2019 Feb;18(2):389-398. doi: 10.1158/1535-7163.MCT-18-0537. Epub 2018 Nov 26. Mol Cancer Ther. 2019. PMID: 30478151 Free PMC article.
Collagen Remodeling in the Hypoxic Tumor-Mesothelial Niche Promotes Ovarian Cancer Metastasis.
Natarajan S, Foreman KM, Soriano MI, Rossen NS, Shehade H, Fregoso DR, Eggold JT, Krishnan V, Dorigo O, Krieg AJ, Heilshorn SC, Sinha S, Fuh KC, Rankin EB. Natarajan S, et al. Among authors: fuh kc. Cancer Res. 2019 May 1;79(9):2271-2284. doi: 10.1158/0008-5472.CAN-18-2616. Epub 2019 Mar 12. Cancer Res. 2019. PMID: 30862717 Free PMC article.
S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma.
Xiao Y, Zhao H, Tian L, Nolley R, Diep AN, Ernst A, Fuh KC, Miao YR, von Eyben R, Leppert JT, Brooks JD, Peehl DM, Giaccia AJ, Rankin EB. Xiao Y, et al. Among authors: fuh kc. Cancer Res. 2019 Nov 15;79(22):5758-5768. doi: 10.1158/0008-5472.CAN-19-1366. Epub 2019 Oct 4. Cancer Res. 2019. PMID: 31585940 Free PMC article.
GAS6/AXL Inhibition Enhances Ovarian Cancer Sensitivity to Chemotherapy and PARP Inhibition through Increased DNA Damage and Enhanced Replication Stress.
Mullen MM, Lomonosova E, Toboni MD, Oplt A, Cybulla E, Blachut B, Zhao P, Noia H, Wilke D, Rankin EB, Kuroki LM, Hagemann AR, Hagemann IS, McCourt CK, Thaker PH, Mutch DG, Powell MA, Mosammaparast N, Vindigni A, Fuh KC. Mullen MM, et al. Among authors: fuh kc. Mol Cancer Res. 2022 Feb;20(2):265-279. doi: 10.1158/1541-7786.MCR-21-0302. Epub 2021 Oct 20. Mol Cancer Res. 2022. PMID: 34670865 Free PMC article.
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