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One piece of the puzzle: Population pharmacokinetics of FVIII during perioperative Haemate P® /Humate P® treatment in von Willebrand disease patients.
de Jager NCB, Bukkems LH, Heijdra JM, Hazendonk CHCAM, Fijnvandraat K, Meijer K, Eikenboom J, Laros-van Gorkom BAP, Leebeek FWG, Cnossen MH, Mathôt RAA; OPTI-CLOT group. de Jager NCB, et al. Among authors: bukkems lh. J Thromb Haemost. 2020 Feb;18(2):295-305. doi: 10.1111/jth.14652. Epub 2019 Oct 21. J Thromb Haemost. 2020. PMID: 31557387 Free PMC article.
A Novel, Enriched Population Pharmacokinetic Model for Recombinant Factor VIII-Fc Fusion Protein Concentrate in Hemophilia A Patients.
Bukkems LH, Heijdra JM, Mathias M, Collins PW, Hay CRM, Tait RC, Mangles S, Myers B, Evans G, Bailiff B, Curry N, Payne J, Austin S, Goedhart TMHJ, Leebeek FWG, Meijer K, Fijnvandraat K, Chowdary P, Mathôt RAA, Cnossen MH; for UK-EHL Outcomes Registry OPTI-CLOT Collaboration. Bukkems LH, et al. Thromb Haemost. 2020 May;120(5):747-757. doi: 10.1055/s-0040-1709522. Epub 2020 May 5. Thromb Haemost. 2020. PMID: 32369846
von Willebrand Factor and Factor VIII Clearance in Perioperative Hemophilia A Patients.
van Moort I, Bukkems LH, Heijdra JM, Schutgens REG, Laros-van Gorkom BAP, Nieuwenhuizen L, van der Meer FJM, Fijnvandraat K, Ypma P, de Maat MPM, Leebeek FWG, Meijer K, Eikenboom J, Mathôt RAA, Cnossen MH; OPTI-CLOT Study Group. van Moort I, et al. Among authors: bukkems lh. Thromb Haemost. 2020 Jul;120(7):1056-1065. doi: 10.1055/s-0040-1710591. Epub 2020 Jun 1. Thromb Haemost. 2020. PMID: 32480417 Clinical Trial.
30 results