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The Chemical Synthesis of Knob Domain Antibody Fragments.
Macpherson A, Birtley JR, Broadbridge RJ, Brady K, Schulze MED, Tang Y, Joyce C, Saunders K, Bogle G, Horton J, Kelm S, Taylor RD, Franklin RJ, Selby MD, Laabei M, Wonfor T, Hold A, Stanley P, Vadysirisack D, Shi J, van den Elsen J, Lawson ADG. Macpherson A, et al. Among authors: hold a. ACS Chem Biol. 2021 Sep 17;16(9):1757-1769. doi: 10.1021/acschembio.1c00472. Epub 2021 Aug 18. ACS Chem Biol. 2021. PMID: 34406751 Free article.
Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives.
Tisi D, Chiarparin E, Tamanini E, Pathuri P, Coyle JE, Hold A, Holding FP, Amin N, Martin AC, Rich SJ, Berdini V, Yon J, Acklam P, Burke R, Drouin L, Harmer JE, Jeganathan F, van Montfort RL, Newbatt Y, Tortorici M, Westlake M, Wood A, Hoelder S, Heightman TD. Tisi D, et al. Among authors: hold a. ACS Chem Biol. 2016 Nov 18;11(11):3093-3105. doi: 10.1021/acschembio.6b00308. Epub 2016 Sep 27. ACS Chem Biol. 2016. PMID: 27571355
Atropisomeric small molecule Bcl-2 ligands: determination of bioactive conformation.
Porter J, Payne A, Whitcombe I, de Candole B, Ford D, Garlish R, Hold A, Hutchinson B, Trevitt G, Turner J, Edwards C, Watkins C, Davis J, Stubberfield C. Porter J, et al. Among authors: hold a. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1767-72. doi: 10.1016/j.bmcl.2009.01.071. Epub 2009 Jan 27. Bioorg Med Chem Lett. 2009. PMID: 19217289
Identification of differential protein binding affinities in an atropisomeric pharmaceutical compound by noncovalent mass spectrometry, equilibrium dialysis, and nuclear magnetic resonance.
Maple HJ, Garlish RA, Whitcombe I, Hold A, Prosser CE, Ford D, Mackenzie H, Crosby J, Porter J, Taylor RJ, Crump MP. Maple HJ, et al. Among authors: hold a. Anal Chem. 2013 Jun 18;85(12):5958-64. doi: 10.1021/ac400760p. Epub 2013 Jun 3. Anal Chem. 2013. PMID: 23697870
24 results