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The Chemical Synthesis of Knob Domain Antibody Fragments.
Macpherson A, Birtley JR, Broadbridge RJ, Brady K, Schulze MED, Tang Y, Joyce C, Saunders K, Bogle G, Horton J, Kelm S, Taylor RD, Franklin RJ, Selby MD, Laabei M, Wonfor T, Hold A, Stanley P, Vadysirisack D, Shi J, van den Elsen J, Lawson ADG. Macpherson A, et al. Among authors: horton j. ACS Chem Biol. 2021 Sep 17;16(9):1757-1769. doi: 10.1021/acschembio.1c00472. Epub 2021 Aug 18. ACS Chem Biol. 2021. PMID: 34406751 Free article.
New benzylureas as a novel series of potent, nonpeptidic vasopressin V2 receptor agonists.
Yea CM, Allan CE, Ashworth DM, Barnett J, Baxter AJ, Broadbridge JD, Franklin RJ, Hampton SL, Hudson P, Horton JA, Jenkins PD, Penson AM, Pitt GR, Rivière P, Robson PA, Rooker DP, Semple G, Sheppard A, Haigh RM, Roe MB. Yea CM, et al. Among authors: horton ja. J Med Chem. 2008 Dec 25;51(24):8124-34. doi: 10.1021/jm8008162. J Med Chem. 2008. PMID: 19053774
Reciprocal Regulation of Cardiac β-Oxidation and Pyruvate Dehydrogenase by Insulin.
Elnwasany A, Ewida HA, Menendez-Montes I, Mizerska M, Fu X, Kim CW, Horton JD, Burgess SC, Rothermel BA, Szweda PA, Szweda LI. Elnwasany A, et al. Among authors: horton jd. J Biol Chem. 2024 May 23:107412. doi: 10.1016/j.jbc.2024.107412. Online ahead of print. J Biol Chem. 2024. PMID: 38796064 Free article.
Quinoline-based compounds can inhibit diverse enzymes that act on DNA.
Zhou J, Chen Q, Ren R, Yang J, Liu B, Horton JR, Chang C, Li C, Maksoud L, Yang Y, Rotili D, Zhang X, Blumenthal RM, Chen T, Gao Y, Valente S, Mai A, Cheng X. Zhou J, et al. Among authors: horton jr. bioRxiv [Preprint]. 2024 Apr 3:2024.04.03.587980. doi: 10.1101/2024.04.03.587980. bioRxiv. 2024. PMID: 38617249 Free PMC article. Preprint.
Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.
Deja S, Fletcher JA, Kim CW, Kucejova B, Fu X, Mizerska M, Villegas M, Pudelko-Malik N, Browder N, Inigo-Vollmer M, Menezes CJ, Mishra P, Berglund ED, Browning JD, Thyfault JP, Young JD, Horton JD, Burgess SC. Deja S, et al. Among authors: horton jd. Cell Metab. 2024 May 7;36(5):1088-1104.e12. doi: 10.1016/j.cmet.2024.02.004. Epub 2024 Mar 5. Cell Metab. 2024. PMID: 38447582 Free article.
1,945 results