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Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery.
Di Franco S, Bianca P, Sardina DS, Turdo A, Gaggianesi M, Veschi V, Nicotra A, Mangiapane LR, Lo Iacono M, Pillitteri I, van Hooff S, Martorana F, Motta G, Gulotta E, Lentini VL, Martorana E, Fiori ME, Vieni S, Bongiorno MR, Giannone G, Giuffrida D, Memeo L, Colarossi L, Mare M, Vigneri P, Todaro M, De Maria R, Medema JP, Stassi G. Di Franco S, et al. Among authors: medema jp. Nat Commun. 2021 Aug 18;12(1):5006. doi: 10.1038/s41467-021-25333-9. Nat Commun. 2021. PMID: 34408135 Free PMC article.
PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells.
Mangiapane LR, Nicotra A, Turdo A, Gaggianesi M, Bianca P, Di Franco S, Sardina DS, Veschi V, Signore M, Beyes S, Fagnocchi L, Fiori ME, Bongiorno MR, Lo Iacono M, Pillitteri I, Ganduscio G, Gulotta G, Medema JP, Zippo A, Todaro M, De Maria R, Stassi G. Mangiapane LR, et al. Among authors: medema jp. Gut. 2022 Jan;71(1):119-128. doi: 10.1136/gutjnl-2020-323553. Epub 2021 Jan 12. Gut. 2022. PMID: 33436496 Free PMC article.
Betulinic Acid Kills Colon Cancer Stem Cells.
Potze L, di Franco S, Kessler JH, Stassi G, Medema JP. Potze L, et al. Among authors: medema jp. Curr Stem Cell Res Ther. 2016;11(5):427-33. doi: 10.2174/1574888x11666151203223512. Curr Stem Cell Res Ther. 2016. PMID: 26647913
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.
Vermeulen L, De Sousa E Melo F, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP. Vermeulen L, et al. Among authors: medema jp. Nat Cell Biol. 2010 May;12(5):468-76. doi: 10.1038/ncb2048. Epub 2010 Apr 25. Nat Cell Biol. 2010. PMID: 20418870
Colon cancer stem cells: promise of targeted therapy.
Todaro M, Francipane MG, Medema JP, Stassi G. Todaro M, et al. Among authors: medema jp. Gastroenterology. 2010 Jun;138(6):2151-62. doi: 10.1053/j.gastro.2009.12.063. Gastroenterology. 2010. PMID: 20420952 Review.
IL-4-mediated drug resistance in colon cancer stem cells.
Todaro M, Perez Alea M, Scopelliti A, Medema JP, Stassi G. Todaro M, et al. Among authors: medema jp. Cell Cycle. 2008 Feb 1;7(3):309-13. doi: 10.4161/cc.7.3.5389. Epub 2007 Nov 30. Cell Cycle. 2008. PMID: 18235245 Review.
ΔNp63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis.
Di Franco S, Turdo A, Benfante A, Colorito ML, Gaggianesi M, Apuzzo T, Kandimalla R, Chinnici A, Barcaroli D, Mangiapane LR, Pistone G, Vieni S, Gulotta E, Dieli F, Medema JP, Stassi G, De Laurenzi V, Todaro M. Di Franco S, et al. Among authors: medema jp. Oncotarget. 2016 Aug 23;7(34):54157-54173. doi: 10.18632/oncotarget.11022. Oncotarget. 2016. PMID: 27494839 Free PMC article.
250 results