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Metabolic decisions in development and disease-a Keystone Symposia report.
Cable J, Pourquié O, Wellen KE, Finley LWS, Aulehla A, Gould AP, Teleman A, Tu WB, Garrett WS, Miguel-Aliaga I, Perrimon N, Hooper LV, Walhout AJM, Wei W, Alexandrov T, Erez A, Ralser M, Rabinowitz JD, Hemalatha A, Gutiérrez-Pérez P, Chandel NS, Rutter J, Locasale JW, Landoni JC, Christofk H. Cable J, et al. Among authors: wellen ke. Ann N Y Acad Sci. 2021 Dec;1506(1):55-73. doi: 10.1111/nyas.14678. Epub 2021 Aug 19. Ann N Y Acad Sci. 2021. PMID: 34414571 Review.
Dysregulated metabolism contributes to oncogenesis.
Hirschey MD, DeBerardinis RJ, Diehl AME, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, Michelotti G, Muralidhar V, Murphy MP, Pedersen PL, Poore B, Raffaghello L, Rathmell JC, Sivanand S, Vander Heiden MG, Wellen KE; Target Validation Team. Hirschey MD, et al. Among authors: wellen ke. Semin Cancer Biol. 2015 Dec;35 Suppl:S129-S150. doi: 10.1016/j.semcancer.2015.10.002. Epub 2015 Oct 8. Semin Cancer Biol. 2015. PMID: 26454069 Free PMC article. Review.
Metabolic control of methylation and acetylation.
Su X, Wellen KE, Rabinowitz JD. Su X, et al. Among authors: wellen ke. Curr Opin Chem Biol. 2016 Feb;30:52-60. doi: 10.1016/j.cbpa.2015.10.030. Epub 2015 Nov 28. Curr Opin Chem Biol. 2016. PMID: 26629854 Free PMC article. Review.
Metabolic control of epigenetics in cancer.
Kinnaird A, Zhao S, Wellen KE, Michelakis ED. Kinnaird A, et al. Among authors: wellen ke. Nat Rev Cancer. 2016 Nov;16(11):694-707. doi: 10.1038/nrc.2016.82. Epub 2016 Sep 16. Nat Rev Cancer. 2016. PMID: 27634449 Review.
Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis.
McDonald OG, Li X, Saunders T, Tryggvadottir R, Mentch SJ, Warmoes MO, Word AE, Carrer A, Salz TH, Natsume S, Stauffer KM, Makohon-Moore A, Zhong Y, Wu H, Wellen KE, Locasale JW, Iacobuzio-Donahue CA, Feinberg AP. McDonald OG, et al. Among authors: wellen ke. Nat Genet. 2017 Mar;49(3):367-376. doi: 10.1038/ng.3753. Epub 2017 Jan 16. Nat Genet. 2017. PMID: 28092686 Free PMC article.
Metabolic Signaling to the Nucleus in Cancer.
Campbell SL, Wellen KE. Campbell SL, et al. Among authors: wellen ke. Mol Cell. 2018 Aug 2;71(3):398-408. doi: 10.1016/j.molcel.2018.07.015. Mol Cell. 2018. PMID: 30075141 Free article. Review.
Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals.
Liu X, Cooper DE, Cluntun AA, Warmoes MO, Zhao S, Reid MA, Liu J, Lund PJ, Lopes M, Garcia BA, Wellen KE, Kirsch DG, Locasale JW. Liu X, et al. Among authors: wellen ke. Cell. 2018 Oct 4;175(2):502-513.e13. doi: 10.1016/j.cell.2018.08.040. Epub 2018 Sep 20. Cell. 2018. PMID: 30245009 Free PMC article.
More Metabolism!
Olzmann JA, Fendt SM, Shah YM, Vousden K, Chandel N, Horng T, Danial N, Tu B, Christofk H, Vander Heiden MG, Wellen K. Olzmann JA, et al. Mol Cell. 2021 Sep 16;81(18):3659-3664. doi: 10.1016/j.molcel.2021.08.040. Mol Cell. 2021. PMID: 34547228 Free article.
84 results