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Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity.
Christo SN, Evrard M, Park SL, Gandolfo LC, Burn TN, Fonseca R, Newman DM, Alexandre YO, Collins N, Zamudio NM, Souza-Fonseca-Guimaraes F, Pellicci DG, Chisanga D, Shi W, Bartholin L, Belz GT, Huntington ND, Lucas A, Lucas M, Mueller SN, Heath WR, Ginhoux F, Speed TP, Carbone FR, Kallies A, Mackay LK. Christo SN, et al. Among authors: park sl. Nat Immunol. 2021 Sep;22(9):1140-1151. doi: 10.1038/s41590-021-01004-1. Epub 2021 Aug 23. Nat Immunol. 2021. PMID: 34426691
PD-1: always on my mind.
Park SL, Mackay LK. Park SL, et al. Immunol Cell Biol. 2017 Nov;95(10):857-858. doi: 10.1038/icb.2017.69. Epub 2017 Sep 26. Immunol Cell Biol. 2017. PMID: 28948981 No abstract available.
Tissue-resident memory CD8+ T cells promote melanoma-immune equilibrium in skin.
Park SL, Buzzai A, Rautela J, Hor JL, Hochheiser K, Effern M, McBain N, Wagner T, Edwards J, McConville R, Wilmott JS, Scolyer RA, Tüting T, Palendira U, Gyorki D, Mueller SN, Huntington ND, Bedoui S, Hölzel M, Mackay LK, Waithman J, Gebhardt T. Park SL, et al. Nature. 2019 Jan;565(7739):366-371. doi: 10.1038/s41586-018-0812-9. Epub 2018 Dec 31. Nature. 2019. PMID: 30598548
TCF-1 limits the formation of Tc17 cells via repression of the MAF-RORγt axis.
Mielke LA, Liao Y, Clemens EB, Firth MA, Duckworth B, Huang Q, Almeida FF, Chopin M, Koay HF, Bell CA, Hediyeh-Zadeh S, Park SL, Raghu D, Choi J, Putoczki TL, Hodgkin PD, Franks AE, Mackay LK, Godfrey DI, Davis MJ, Xue HH, Bryant VL, Kedzierska K, Shi W, Belz GT. Mielke LA, et al. Among authors: park sl. J Exp Med. 2019 Jul 1;216(7):1682-1699. doi: 10.1084/jem.20181778. Epub 2019 May 29. J Exp Med. 2019. PMID: 31142588 Free PMC article.
Tissue-resident memory T cells orchestrate tumour-immune equilibrium.
Park SL, Mackay LK, Waithman J, Gebhardt T. Park SL, et al. Cell Stress. 2019 Apr 26;3(5):162-164. doi: 10.15698/cst2019.05.187. Cell Stress. 2019. PMID: 31225511 Free PMC article.
However, the mechanisms through which these cells mediate cancer protection are poorly understood. In our recent study (Park SL et al, Nature 565(7739), 2019) we developed a melanoma model that allowed us to identify a critical role for T(RM) cells in the establishm …
However, the mechanisms through which these cells mediate cancer protection are poorly understood. In our recent study (Park SL
Bhlhe40 Keeps Resident T Cells Too Fit to Quit.
Park SL, Mackay LK. Park SL, et al. Immunity. 2019 Sep 17;51(3):418-420. doi: 10.1016/j.immuni.2019.08.016. Immunity. 2019. PMID: 31533052 Free article.
198 results