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Hypercholesterolemia and 27-Hydroxycholesterol Increase S100A8 and RAGE Expression in the Brain: a Link Between Cholesterol, Alarmins, and Neurodegeneration.
Loera-Valencia R, Ismail MA, Goikolea J, Lodeiro M, Mateos L, Björkhem I, Puerta E, Romão MA, Gomes CM, Merino-Serrais P, Maioli S, Cedazo-Minguez A. Loera-Valencia R, et al. Among authors: bjorkhem i. Mol Neurobiol. 2021 Dec;58(12):6063-6076. doi: 10.1007/s12035-021-02521-8. Epub 2021 Aug 27. Mol Neurobiol. 2021. PMID: 34449045 Free PMC article.
Oxysterols and neurodegenerative diseases.
Björkhem I, Cedazo-Minguez A, Leoni V, Meaney S. Björkhem I, et al. Mol Aspects Med. 2009 Jun;30(3):171-9. doi: 10.1016/j.mam.2009.02.001. Epub 2009 Feb 25. Mol Aspects Med. 2009. PMID: 19248803 Review.
27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation.
Ismail MA, Mateos L, Maioli S, Merino-Serrais P, Ali Z, Lodeiro M, Westman E, Leitersdorf E, Gulyás B, Olof-Wahlund L, Winblad B, Savitcheva I, Björkhem I, Cedazo-Mínguez A. Ismail MA, et al. Among authors: bjorkhem i. J Exp Med. 2017 Mar 6;214(3):699-717. doi: 10.1084/jem.20160534. Epub 2017 Feb 17. J Exp Med. 2017. PMID: 28213512 Free PMC article.
Activity-regulated cytoskeleton-associated protein in rodent brain is down-regulated by high fat diet in vivo and by 27-hydroxycholesterol in vitro.
Mateos L, Akterin S, Gil-Bea FJ, Spulber S, Rahman A, Björkhem I, Schultzberg M, Flores-Morales A, Cedazo-Mínguez A. Mateos L, et al. Among authors: bjorkhem i. Brain Pathol. 2009 Jan;19(1):69-80. doi: 10.1111/j.1750-3639.2008.00174.x. Epub 2008 May 23. Brain Pathol. 2009. PMID: 18503570 Free PMC article.
561 results