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Genomic instability in the naturally and prematurely aged myocardium.
De Majo F, Martens L, Hegenbarth JC, Rühle F, Hamczyk MR, Nevado RM, Andrés V, Hilbold E, Bär C, Thum T, de Boer M, Duncker DJ, Schroen B, Armand AS, Stoll M, De Windt LJ. De Majo F, et al. Among authors: thum t. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2022974118. doi: 10.1073/pnas.2022974118. Proc Natl Acad Sci U S A. 2021. PMID: 34465617 Free PMC article.
Macrophage microRNA-155 promotes cardiac hypertrophy and failure.
Heymans S, Corsten MF, Verhesen W, Carai P, van Leeuwen RE, Custers K, Peters T, Hazebroek M, Stöger L, Wijnands E, Janssen BJ, Creemers EE, Pinto YM, Grimm D, Schürmann N, Vigorito E, Thum T, Stassen F, Yin X, Mayr M, de Windt LJ, Lutgens E, Wouters K, de Winther MP, Zacchigna S, Giacca M, van Bilsen M, Papageorgiou AP, Schroen B. Heymans S, et al. Among authors: thum t. Circulation. 2013 Sep 24;128(13):1420-32. doi: 10.1161/CIRCULATIONAHA.112.001357. Epub 2013 Aug 16. Circulation. 2013. PMID: 23956210
Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure.
Dirkx E, Gladka MM, Philippen LE, Armand AS, Kinet V, Leptidis S, El Azzouzi H, Salic K, Bourajjaj M, da Silva GJ, Olieslagers S, van der Nagel R, de Weger R, Bitsch N, Kisters N, Seyen S, Morikawa Y, Chanoine C, Heymans S, Volders PG, Thum T, Dimmeler S, Cserjesi P, Eschenhagen T, da Costa Martins PA, De Windt LJ. Dirkx E, et al. Among authors: thum t. Nat Cell Biol. 2013 Nov;15(11):1282-93. doi: 10.1038/ncb2866. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161931
Long noncoding RNAs in cardiac development and ageing.
Devaux Y, Zangrando J, Schroen B, Creemers EE, Pedrazzini T, Chang CP, Dorn GW 2nd, Thum T, Heymans S; Cardiolinc network. Devaux Y, et al. Among authors: thum t. Nat Rev Cardiol. 2015 Jul;12(7):415-25. doi: 10.1038/nrcardio.2015.55. Epub 2015 Apr 7. Nat Rev Cardiol. 2015. PMID: 25855606 Review.
Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure.
Mayer SC, Gilsbach R, Preissl S, Monroy Ordonez EB, Schnick T, Beetz N, Lother A, Rommel C, Ihle H, Bugger H, Rühle F, Schrepper A, Schwarzer M, Heilmann C, Bönisch U, Gupta SK, Wilpert J, Kretz O, von Elverfeldt D, Orth J, Aktories K, Beyersdorf F, Bode C, Stiller B, Krüger M, Thum T, Doenst T, Stoll M, Hein L. Mayer SC, et al. Among authors: thum t. Circ Res. 2015 Sep 11;117(7):622-33. doi: 10.1161/CIRCRESAHA.115.306721. Epub 2015 Jul 20. Circ Res. 2015. PMID: 26195221 Free PMC article.
RNA Profiling in Human and Murine Transplanted Hearts: Identification and Validation of Therapeutic Targets for Acute Cardiac and Renal Allograft Rejection.
Van Aelst LN, Summer G, Li S, Gupta SK, Heggermont W, De Vusser K, Carai P, Naesens M, Van Cleemput J, Van de Werf F, Vanhaecke J, Thum T, Waer M, Papageorgiou AP, Schroen B, Heymans S. Van Aelst LN, et al. Among authors: thum t. Am J Transplant. 2016 Jan;16(1):99-110. doi: 10.1111/ajt.13421. Epub 2015 Aug 6. Am J Transplant. 2016. PMID: 26249758 Free PMC article.
Long noncoding RNA Chast promotes cardiac remodeling.
Viereck J, Kumarswamy R, Foinquinos A, Xiao K, Avramopoulos P, Kunz M, Dittrich M, Maetzig T, Zimmer K, Remke J, Just A, Fendrich J, Scherf K, Bolesani E, Schambach A, Weidemann F, Zweigerdt R, de Windt LJ, Engelhardt S, Dandekar T, Batkai S, Thum T. Viereck J, et al. Among authors: thum t. Sci Transl Med. 2016 Feb 17;8(326):326ra22. doi: 10.1126/scitranslmed.aaf1475. Sci Transl Med. 2016. PMID: 26888430
496 results