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Genome-wide association study of frontotemporal dementia identifies a C9ORF72 haplotype with a median of 12-G4C2 repeats that predisposes to pathological repeat expansions.
Reus LM, Jansen IE, Mol MO, van Ruissen F, van Rooij J, van Schoor NM, Tesi N, Reinders MJT, Huisman MA, Holstege H, Visser PJ, de Boer SCM, Hulsman M, Ahmad S, Amin N, Uitterlinden AG, Ikram A, van Duijn CM, Seelaar H, Ramakers IHGB, Verhey FRJ, van der Lugt A, Claassen JAHR, Jan Biessels G, De Deyn PP, Scheltens P, van der Flier WM, van Swieten JC, Pijnenburg YAL, van der Lee SJ. Reus LM, et al. Among authors: huisman ma. Transl Psychiatry. 2021 Sep 2;11(1):451. doi: 10.1038/s41398-021-01577-3. Transl Psychiatry. 2021. PMID: 34475377 Free PMC article.
The Longitudinal Aging Study Amsterdam: cohort update 2016 and major findings.
Hoogendijk EO, Deeg DJ, Poppelaars J, van der Horst M, Broese van Groenou MI, Comijs HC, Pasman HR, van Schoor NM, Suanet B, Thomése F, van Tilburg TG, Visser M, Huisman M. Hoogendijk EO, et al. Eur J Epidemiol. 2016 Sep;31(9):927-45. doi: 10.1007/s10654-016-0192-0. Epub 2016 Aug 20. Eur J Epidemiol. 2016. PMID: 27544533 Free PMC article.
Modifiable Risk Factors for Prevention of Dementia in Midlife, Late Life and the Oldest-Old: Validation of the LIBRA Index.
Vos SJB, van Boxtel MPJ, Schiepers OJG, Deckers K, de Vugt M, Carrière I, Dartigues JF, Peres K, Artero S, Ritchie K, Galluzzo L, Scafato E, Frisoni GB, Huisman M, Comijs HC, Sacuiu SF, Skoog I, Irving K, O'Donnell CA, Verhey FRJ, Visser PJ, Köhler S. Vos SJB, et al. J Alzheimers Dis. 2017;58(2):537-547. doi: 10.3233/JAD-161208. J Alzheimers Dis. 2017. PMID: 28453475
Age dependency of risk factors for cognitive decline.
Legdeur N, Heymans MW, Comijs HC, Huisman M, Maier AB, Visser PJ. Legdeur N, et al. BMC Geriatr. 2018 Aug 20;18(1):187. doi: 10.1186/s12877-018-0876-2. BMC Geriatr. 2018. PMID: 30126373 Free PMC article.
Centenarian controls increase variant effect sizes by an average twofold in an extreme case-extreme control analysis of Alzheimer's disease.
Tesi N, van der Lee SJ, Hulsman M, Jansen IE, Stringa N, van Schoor N, Meijers-Heijboer H, Huisman M, Scheltens P, Reinders MJT, van der Flier WM, Holstege H. Tesi N, et al. Eur J Hum Genet. 2019 Feb;27(2):244-253. doi: 10.1038/s41431-018-0273-5. Epub 2018 Sep 26. Eur J Hum Genet. 2019. PMID: 30258121 Free PMC article.
The Longitudinal Aging Study Amsterdam: cohort update 2019 and additional data collections.
Hoogendijk EO, Deeg DJH, de Breij S, Klokgieters SS, Kok AAL, Stringa N, Timmermans EJ, van Schoor NM, van Zutphen EM, van der Horst M, Poppelaars J, Malhoe P, Huisman M. Hoogendijk EO, et al. Eur J Epidemiol. 2020 Jan;35(1):61-74. doi: 10.1007/s10654-019-00541-2. Epub 2019 Jul 25. Eur J Epidemiol. 2020. PMID: 31346890 Free PMC article.
A meta-analysis of genome-wide association studies identifies multiple longevity genes.
Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM. Deelen J, et al. Among authors: huisman m. Nat Commun. 2019 Aug 14;10(1):3669. doi: 10.1038/s41467-019-11558-2. Nat Commun. 2019. PMID: 31413261 Free PMC article.
Physical Activity as Moderator of the Association Between APOE and Cognitive Decline in Older Adults: Results from Three Longitudinal Cohort Studies.
Stringa N, van Schoor NM, Milaneschi Y, Ikram MA, Del Panta V, Koolhaas CM, Voortman T, Bandinelli S, Wolters FJ, Huisman M. Stringa N, et al. Among authors: huisman m. J Gerontol A Biol Sci Med Sci. 2020 Sep 25;75(10):1880-1886. doi: 10.1093/gerona/glaa054. J Gerontol A Biol Sci Med Sci. 2020. PMID: 32110803 Free PMC article.
209 results