Haddad D - Search Results

1

Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration.

Linsley JW, Shah K, Castello N, Chan M, Haddad D, Doric Z, Wang S, Leks W, Mancini J, Oza V, Javaherian A, Nakamura K, Kokel D, Finkbeiner S. Linsley JW, et al. Among authors: haddad d. Nat Commun. 2021 Sep 6;12(1):5284. doi: 10.1038/s41467-021-25549-9. Nat Commun. 2021. PMID: 34489414 Free PMC article.

2

Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease.

Haddad D, Nakamura K. Haddad D, et al. FEBS Lett. 2015 Dec 21;589(24 Pt A):3702-13. doi: 10.1016/j.febslet.2015.10.021. Epub 2015 Oct 23. FEBS Lett. 2015. PMID: 26526613 Free PMC article. Review.

3

PINK1-Based Screen Shines Light on Autophagy Enhancers for Parkinson's Disease.

Haddad D, Nakamura K. Haddad D, et al. Cell Chem Biol. 2017 Apr 20;24(4):429-430. doi: 10.1016/j.chembiol.2017.04.002. Cell Chem Biol. 2017. PMID: 28431223 Free PMC article.

4

Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity.

Shields LY, Li H, Nguyen K, Kim H, Doric Z, Garcia JH, Gill TM, Haddad D, Vossel K, Calvert M, Nakamura K. Shields LY, et al. Among authors: haddad d. J Biol Chem. 2021 Jan-Jun;296:100469. doi: 10.1016/j.jbc.2021.100469. Epub 2021 Feb 25. J Biol Chem. 2021. PMID: 33639169 Free PMC article.

5

The role of mitochondrially derived ATP in synaptic vesicle recycling.

Pathak D, Shields LY, Mendelsohn BA, Haddad D, Lin W, Gerencser AA, Kim H, Brand MD, Edwards RH, Nakamura K. Pathak D, et al. Among authors: haddad d. J Biol Chem. 2015 Sep 11;290(37):22325-36. doi: 10.1074/jbc.M115.656405. Epub 2015 Jun 30. J Biol Chem. 2015. PMID: 26126824 Free PMC article.

6

Isoflurane inhibition of endocytosis is an anesthetic mechanism of action.

Jung S, Zimin PI, Woods CB, Kayser EB, Haddad D, Reczek CR, Nakamura K, Ramirez JM, Sedensky MM, Morgan PG. Jung S, et al. Among authors: haddad d. Curr Biol. 2022 Jul 25;32(14):3016-3032.e3. doi: 10.1016/j.cub.2022.05.037. Epub 2022 Jun 9. Curr Biol. 2022. PMID: 35688155 Free PMC article.

7

Shields LY, Kim H, Zhu L, Haddad D, Berthet A, Pathak D, Lam M, Ponnusamy R, Diaz-Ramirez LG, Gill TM, Sesaki H, Mucke L, Nakamura K. Shields LY, et al. Among authors: haddad d. Cell Death Dis. 2015 Apr 16;6(4):e1725. doi: 10.1038/cddis.2015.94. Cell Death Dis. 2015. PMID: 25880092 Free PMC article.

8

The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants.

Vilain S, Esposito G, Haddad D, Schaap O, Dobreva MP, Vos M, Van Meensel S, Morais VA, De Strooper B, Verstreken P. Vilain S, et al. Among authors: haddad d. PLoS Genet. 2012 Jan;8(1):e1002456. doi: 10.1371/journal.pgen.1002456. Epub 2012 Jan 5. PLoS Genet. 2012. PMID: 22242018 Free PMC article.

9

Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.

Vos M, Esposito G, Edirisinghe JN, Vilain S, Haddad DM, Slabbaert JR, Van Meensel S, Schaap O, De Strooper B, Meganathan R, Morais VA, Verstreken P. Vos M, et al. Science. 2012 Jun 8;336(6086):1306-10. doi: 10.1126/science.1218632. Epub 2012 May 10. Science. 2012. PMID: 22582012 Free article.

10

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function.

Morais VA, Verstreken P, Roethig A, Smet J, Snellinx A, Vanbrabant M, Haddad D, Frezza C, Mandemakers W, Vogt-Weisenhorn D, Van Coster R, Wurst W, Scorrano L, De Strooper B. Morais VA, et al. Among authors: haddad d. EMBO Mol Med. 2009 May;1(2):99-111. doi: 10.1002/emmm.200900006. EMBO Mol Med. 2009. PMID: 20049710 Free PMC article.

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