Nakamura K - Search Results

1

Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration.

Linsley JW, Shah K, Castello N, Chan M, Haddad D, Doric Z, Wang S, Leks W, Mancini J, Oza V, Javaherian A, Nakamura K, Kokel D, Finkbeiner S. Linsley JW, et al. Among authors: nakamura k. Nat Commun. 2021 Sep 6;12(1):5284. doi: 10.1038/s41467-021-25549-9. Nat Commun. 2021. PMID: 34489414 Free PMC article.

2

Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein.

Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH. Nakamura K, et al. J Biol Chem. 2011 Jun 10;286(23):20710-26. doi: 10.1074/jbc.M110.213538. Epub 2011 Apr 13. J Biol Chem. 2011. PMID: 21489994 Free PMC article.

3

Energy failure: does it contribute to neurodegeneration?

Pathak D, Berthet A, Nakamura K. Pathak D, et al. Among authors: nakamura k. Ann Neurol. 2013 Oct;74(4):506-16. doi: 10.1002/ana.24014. Ann Neurol. 2013. PMID: 24038413 Free PMC article. Review.

4

Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies.

Skibinski G, Nakamura K, Cookson MR, Finkbeiner S. Skibinski G, et al. Among authors: nakamura k. J Neurosci. 2014 Jan 8;34(2):418-33. doi: 10.1523/JNEUROSCI.2712-13.2014. J Neurosci. 2014. PMID: 24403142 Free PMC article.

5

Shields LY, Kim H, Zhu L, Haddad D, Berthet A, Pathak D, Lam M, Ponnusamy R, Diaz-Ramirez LG, Gill TM, Sesaki H, Mucke L, Nakamura K. Shields LY, et al. Among authors: nakamura k. Cell Death Dis. 2015 Apr 16;6(4):e1725. doi: 10.1038/cddis.2015.94. Cell Death Dis. 2015. PMID: 25880092 Free PMC article.

6

The role of mitochondrially derived ATP in synaptic vesicle recycling.

Pathak D, Shields LY, Mendelsohn BA, Haddad D, Lin W, Gerencser AA, Kim H, Brand MD, Edwards RH, Nakamura K. Pathak D, et al. Among authors: nakamura k. J Biol Chem. 2015 Sep 11;290(37):22325-36. doi: 10.1074/jbc.M115.656405. Epub 2015 Jun 30. J Biol Chem. 2015. PMID: 26126824 Free PMC article.

7

Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease.

Haddad D, Nakamura K. Haddad D, et al. Among authors: nakamura k. FEBS Lett. 2015 Dec 21;589(24 Pt A):3702-13. doi: 10.1016/j.febslet.2015.10.021. Epub 2015 Oct 23. FEBS Lett. 2015. PMID: 26526613 Free PMC article. Review.

8

PINK1-Based Screen Shines Light on Autophagy Enhancers for Parkinson's Disease.

Haddad D, Nakamura K. Haddad D, et al. Among authors: nakamura k. Cell Chem Biol. 2017 Apr 20;24(4):429-430. doi: 10.1016/j.chembiol.2017.04.002. Cell Chem Biol. 2017. PMID: 28431223 Free PMC article.

9

Defining the ATPome reveals cross-optimization of metabolic pathways.

Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K. Bennett NK, et al. Among authors: nakamura jl, nakamura k. Nat Commun. 2020 Aug 28;11(1):4319. doi: 10.1038/s41467-020-18084-6. Nat Commun. 2020. PMID: 32859923 Free PMC article.

10

Mitochondrial fission is a critical modulator of mutant APP-induced neural toxicity.

Shields LY, Li H, Nguyen K, Kim H, Doric Z, Garcia JH, Gill TM, Haddad D, Vossel K, Calvert M, Nakamura K. Shields LY, et al. Among authors: nakamura k. J Biol Chem. 2021 Jan-Jun;296:100469. doi: 10.1016/j.jbc.2021.100469. Epub 2021 Feb 25. J Biol Chem. 2021. PMID: 33639169 Free PMC article.

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