Tripathi S - Search Results

1

Docking and mutagenesis studies lead to improved inhibitor development of ML355 for human platelet 12-lipoxygenase.

Tsai WC, Aleem AM, Tena J, Rivera-Velazquez M, Brah HS, Tripathi S, D'silva M, Nadler JL, Kalyanaraman C, Jacobson MP, Holman T. Tsai WC, et al. Among authors: tripathi s. Bioorg Med Chem. 2021 Sep 15;46:116347. doi: 10.1016/j.bmc.2021.116347. Epub 2021 Aug 4. Bioorg Med Chem. 2021. PMID: 34507163

2

Ligand and Redox Partner Binding Generates a New Conformational State in Cytochrome P450cam (CYP101A1).

Follmer AH, Tripathi S, Poulos TL. Follmer AH, et al. Among authors: tripathi s. J Am Chem Soc. 2019 Feb 13;141(6):2678-2683. doi: 10.1021/jacs.8b13079. Epub 2019 Jan 31. J Am Chem Soc. 2019. PMID: 30672701 Free PMC article.

3

A long lost key opens an ancient lock: Drosophila Myb causes a synthetic multivulval phenotype in nematodes.

Vorster PJ, Goetsch P, Wijeratne TU, Guiley KZ, Andrejka L, Tripathi S, Larson BJ, Rubin SM, Strome S, Lipsick JS. Vorster PJ, et al. Among authors: tripathi s. Biol Open. 2020 May 7;9(5):bio051508. doi: 10.1242/bio.051508. Biol Open. 2020. PMID: 32295830 Free PMC article.

4

DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2-p53 Inhibitor.

Silvestri AP, Zhang Q, Ping Y, Muir EW, Zhao J, Chakka SK, Wang G, Bray WM, Chen W, Fribourgh JL, Tripathi S, He Y, Rubin SM, Satz AL, Pye CR, Kuai L, Su W, Schwochert JA. Silvestri AP, et al. Among authors: tripathi s. ACS Med Chem Lett. 2023 May 5;14(6):820-826. doi: 10.1021/acsmedchemlett.3c00117. eCollection 2023 Jun 8. ACS Med Chem Lett. 2023. PMID: 37312849

5

A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.

Toor JS, Rao AA, McShan AC, Yarmarkovich M, Nerli S, Yamaguchi K, Madejska AA, Nguyen S, Tripathi S, Maris JM, Salama SR, Haussler D, Sgourakis NG. Toor JS, et al. Among authors: tripathi s. Front Immunol. 2018 Jan 30;9:99. doi: 10.3389/fimmu.2018.00099. eCollection 2018. Front Immunol. 2018. PMID: 29441070 Free PMC article.

6

Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch.

Philpott JM, Narasimamurthy R, Ricci CG, Freeberg AM, Hunt SR, Yee LE, Pelofsky RS, Tripathi S, Virshup DM, Partch CL. Philpott JM, et al. Among authors: tripathi s. Elife. 2020 Feb 11;9:e52343. doi: 10.7554/eLife.52343. Elife. 2020. PMID: 32043967 Free PMC article.

7

Crystal structure of cindoxin, the P450cin redox partner.

Madrona Y, Hollingsworth SA, Tripathi S, Fields JB, Rwigema JC, Tobias DJ, Poulos TL. Madrona Y, et al. Among authors: tripathi s. Biochemistry. 2014 Mar 11;53(9):1435-46. doi: 10.1021/bi500010m. Epub 2014 Feb 25. Biochemistry. 2014. PMID: 24533927 Free PMC article.

8

p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.

Guiley KZ, Stevenson JW, Lou K, Barkovich KJ, Kumarasamy V, Wijeratne TU, Bunch KL, Tripathi S, Knudsen ES, Witkiewicz AK, Shokat KM, Rubin SM. Guiley KZ, et al. Among authors: tripathi s. Science. 2019 Dec 13;366(6471):eaaw2106. doi: 10.1126/science.aaw2106. Science. 2019. PMID: 31831640 Free PMC article.

9

Structural, Mechanistic, and Antigenic Characterization of the Human Astrovirus Capsid.

York RL, Yousefi PA, Bogdanoff W, Haile S, Tripathi S, DuBois RM. York RL, et al. Among authors: tripathi s. J Virol. 2015 Dec 9;90(5):2254-63. doi: 10.1128/JVI.02666-15. J Virol. 2015. PMID: 26656707 Free PMC article.

10

Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing.

Fribourgh JL, Srivastava A, Sandate CR, Michael AK, Hsu PL, Rakers C, Nguyen LT, Torgrimson MR, Parico GCG, Tripathi S, Zheng N, Lander GC, Hirota T, Tama F, Partch CL. Fribourgh JL, et al. Among authors: tripathi s. Elife. 2020 Feb 26;9:e55275. doi: 10.7554/eLife.55275. Elife. 2020. PMID: 32101164 Free PMC article.

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