Saez-Rodriguez J - Search Results

1

SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation.

Bidault G, Virtue S, Petkevicius K, Jolin HE, Dugourd A, Guénantin AC, Leggat J, Mahler-Araujo B, Lam BYH, Ma MK, Dale M, Carobbio S, Kaser A, Fallon PG, Saez-Rodriguez J, McKenzie ANJ, Vidal-Puig A. Bidault G, et al. Nat Metab. 2021 Sep;3(9):1150-1162. doi: 10.1038/s42255-021-00440-5. Epub 2021 Sep 16. Nat Metab. 2021. PMID: 34531575 Free PMC article.

2

NADH Shuttling Couples Cytosolic Reductive Carboxylation of Glutamine with Glycolysis in Cells with Mitochondrial Dysfunction.

Gaude E, Schmidt C, Gammage PA, Dugourd A, Blacker T, Chew SP, Saez-Rodriguez J, O'Neill JS, Szabadkai G, Minczuk M, Frezza C. Gaude E, et al. Mol Cell. 2018 Feb 15;69(4):581-593.e7. doi: 10.1016/j.molcel.2018.01.034. Mol Cell. 2018. PMID: 29452638 Free PMC article.

3

Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue.

Pellegrinelli V, Peirce VJ, Howard L, Virtue S, Türei D, Senzacqua M, Frontini A, Dalley JW, Horton AR, Bidault G, Severi I, Whittle A, Rahmouni K, Saez-Rodriguez J, Cinti S, Davies AM, Vidal-Puig A. Pellegrinelli V, et al. Nat Commun. 2018 Nov 26;9(1):4974. doi: 10.1038/s41467-018-07453-x. Nat Commun. 2018. PMID: 30478315 Free PMC article.

4

Converting networks to predictive logic models from perturbation signalling data with CellNOpt.

Gjerga E, Trairatphisan P, Gabor A, Koch H, Chevalier C, Ceccarelli F, Dugourd A, Mitsos A, Saez-Rodriguez J. Gjerga E, et al. Bioinformatics. 2020 Aug 15;36(16):4523-4524. doi: 10.1093/bioinformatics/btaa561. Bioinformatics. 2020. PMID: 32516357 Free PMC article.

5

Footprint-based functional analysis of multiomic data.

Dugourd A, Saez-Rodriguez J. Dugourd A, et al. Curr Opin Syst Biol. 2019 Jun;15:82-90. doi: 10.1016/j.coisb.2019.04.002. Curr Opin Syst Biol. 2019. PMID: 32685770 Free PMC article. Review.

6

Norepinephrine promotes triglyceride storage in macrophages via beta2-adrenergic receptor activation.

Petkevicius K, Bidault G, Virtue S, Jenkins B, van Dierendonck XAMH, Dugourd A, Saez-Rodriguez J, Stienstra R, Koulman A, Vidal-Puig A. Petkevicius K, et al. FASEB J. 2021 Feb;35(2):e21266. doi: 10.1096/fj.202001101R. FASEB J. 2021. PMID: 33484195 Free PMC article.

7

Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses.

Dugourd A, Kuppe C, Sciacovelli M, Gjerga E, Gabor A, Emdal KB, Vieira V, Bekker-Jensen DB, Kranz J, Bindels EMJ, Costa ASH, Sousa A, Beltrao P, Rocha M, Olsen JV, Frezza C, Kramann R, Saez-Rodriguez J. Dugourd A, et al. Mol Syst Biol. 2021 Jan;17(1):e9730. doi: 10.15252/msb.20209730. Mol Syst Biol. 2021. PMID: 33502086 Free PMC article.

8

PHONEMeS: Efficient Modeling of Signaling Networks Derived from Large-Scale Mass Spectrometry Data.

Gjerga E, Dugourd A, Tobalina L, Sousa A, Saez-Rodriguez J. Gjerga E, et al. J Proteome Res. 2021 Apr 2;20(4):2138-2144. doi: 10.1021/acs.jproteome.0c00958. Epub 2021 Mar 8. J Proteome Res. 2021. PMID: 33682416 Free article.

9

Macrophage beta2-adrenergic receptor is dispensable for the adipose tissue inflammation and function.

Petkevicius K, Bidault G, Virtue S, Newland SA, Dale M, Dugourd A, Saez-Rodriguez J, Mallat Z, Vidal-Puig A. Petkevicius K, et al. Mol Metab. 2021 Jun;48:101220. doi: 10.1016/j.molmet.2021.101220. Epub 2021 Mar 25. Mol Metab. 2021. PMID: 33774223 Free PMC article.

10

Systems approach reveals distinct and shared signaling networks of the four PGE₂ receptors in T cells.

Lone AM, Giansanti P, Jørgensen MJ, Gjerga E, Dugourd A, Scholten A, Saez-Rodriguez J, Heck AJR, Taskén K. Lone AM, et al. Sci Signal. 2021 Oct 5;14(703):eabc8579. doi: 10.1126/scisignal.abc8579. Epub 2021 Oct 5. Sci Signal. 2021. PMID: 34609894

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