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Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes.
Immunity. 2021 Oct 12;54(10):2338-2353.e6. doi: 10.1016/j.immuni.2021.08.026. Epub 2021 Sep 16.
Immunity. 2021.
PMID: 34534439
Free PMC article.
Deciphering the immunopeptidome in vivo reveals new tumour antigens.
Jaeger AM, Stopfer LE, Ahn R, Sanders EA, Sandel DA, Freed-Pastor WA, Rideout WM 3rd, Naranjo S, Fessenden T, Nguyen KB, Winter PS, Kohn RE, Westcott PMK, Schenkel JM, Shanahan SL, Shalek AK, Spranger S, White FM, Jacks T.
Jaeger AM, et al. Among authors: shanahan sl.
Nature. 2022 Jul;607(7917):149-155. doi: 10.1038/s41586-022-04839-2. Epub 2022 Jun 15.
Nature. 2022.
PMID: 35705813
Free PMC article.
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Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform.
Naranjo S, Cabana CM, LaFave LM, Romero R, Shanahan SL, Bhutkar A, Westcott PMK, Schenkel JM, Ghosh A, Liao LZ, Del Priore I, Yang D, Jacks T.
Naranjo S, et al. Among authors: shanahan sl.
Genes Dev. 2022 Aug 1;36(15-16):936-949. doi: 10.1101/gad.349659.122. Epub 2022 Sep 29.
Genes Dev. 2022.
PMID: 36175034
Free PMC article.
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A prime editor mouse to model a broad spectrum of somatic mutations in vivo.
Ely ZA, Mathey-Andrews N, Naranjo S, Gould SI, Mercer KL, Newby GA, Cabana CM, Rideout WM 3rd, Jaramillo GC, Khirallah JM, Holland K, Randolph PB, Freed-Pastor WA, Davis JR, Kulstad Z, Westcott PMK, Lin L, Anzalone AV, Horton BL, Pattada NB, Shanahan SL, Ye Z, Spranger S, Xu Q, Sánchez-Rivera FJ, Liu DR, Jacks T.
Ely ZA, et al. Among authors: shanahan sl.
Nat Biotechnol. 2024 Mar;42(3):424-436. doi: 10.1038/s41587-023-01783-y. Epub 2023 May 11.
Nat Biotechnol. 2024.
PMID: 37169967
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Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity.
Westcott PMK, Muyas F, Hauck H, Smith OC, Sacks NJ, Ely ZA, Jaeger AM, Rideout WM 3rd, Zhang D, Bhutkar A, Beytagh MC, Canner DA, Jaramillo GC, Bronson RT, Naranjo S, Jin A, Patten JJ, Cruz AM, Shanahan SL, Cortes-Ciriano I, Jacks T.
Westcott PMK, et al. Among authors: shanahan sl.
Nat Genet. 2023 Oct;55(10):1686-1695. doi: 10.1038/s41588-023-01499-4. Epub 2023 Sep 14.
Nat Genet. 2023.
PMID: 37709863
Free PMC article.
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LC3B phosphorylation regulates FYCO1 binding and directional transport of autophagosomes.
Nieto-Torres JL, Shanahan SL, Chassefeyre R, Chaiamarit T, Zaretski S, Landeras-Bueno S, Verhelle A, Encalada SE, Hansen M.
Nieto-Torres JL, et al. Among authors: shanahan sl.
Curr Biol. 2021 Aug 9;31(15):3440-3449.e7. doi: 10.1016/j.cub.2021.05.052. Epub 2021 Jun 18.
Curr Biol. 2021.
PMID: 34146484
Free PMC article.
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