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Page 1
Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk.
Lake J, Reed X, Langston RG, Nalls MA, Gan-Or Z, Cookson MR, Singleton AB, Blauwendraat C, Leonard HL; International Parkinson's Disease Genomics Consortium (IPDGC). Lake J, et al. Among authors: cookson mr. Mov Disord. 2022 Jan;37(1):95-105. doi: 10.1002/mds.28787. Epub 2021 Sep 20. Mov Disord. 2022. PMID: 34542912 Free PMC article.
Genes and parkinsonism.
Hardy J, Cookson MR, Singleton A. Hardy J, et al. Among authors: cookson mr. Lancet Neurol. 2003 Apr;2(4):221-8. doi: 10.1016/s1474-4422(03)00350-8. Lancet Neurol. 2003. PMID: 12849210 Review.
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin.
Greggio E, Jain S, Kingsbury A, Bandopadhyay R, Lewis P, Kaganovich A, van der Brug MP, Beilina A, Blackinton J, Thomas KJ, Ahmad R, Miller DW, Kesavapany S, Singleton A, Lees A, Harvey RJ, Harvey K, Cookson MR. Greggio E, et al. Among authors: cookson mr. Neurobiol Dis. 2006 Aug;23(2):329-41. doi: 10.1016/j.nbd.2006.04.001. Epub 2006 Jun 5. Neurobiol Dis. 2006. PMID: 16750377
Genetics of Parkinson's disease and parkinsonism.
Hardy J, Cai H, Cookson MR, Gwinn-Hardy K, Singleton A. Hardy J, et al. Among authors: cookson mr. Ann Neurol. 2006 Oct;60(4):389-98. doi: 10.1002/ana.21022. Ann Neurol. 2006. PMID: 17068789 Review.
The R1441C mutation of LRRK2 disrupts GTP hydrolysis.
Lewis PA, Greggio E, Beilina A, Jain S, Baker A, Cookson MR. Lewis PA, et al. Among authors: cookson mr. Biochem Biophys Res Commun. 2007 Jun 8;357(3):668-71. doi: 10.1016/j.bbrc.2007.04.006. Epub 2007 Apr 10. Biochem Biophys Res Commun. 2007. PMID: 17442267 Free PMC article.
Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans.
van de Leemput J, Chandran J, Knight MA, Holtzclaw LA, Scholz S, Cookson MR, Houlden H, Gwinn-Hardy K, Fung HC, Lin X, Hernandez D, Simon-Sanchez J, Wood NW, Giunti P, Rafferty I, Hardy J, Storey E, Gardner RJ, Forrest SM, Fisher EM, Russell JT, Cai H, Singleton AB. van de Leemput J, et al. Among authors: cookson mr. PLoS Genet. 2007 Jun;3(6):e108. doi: 10.1371/journal.pgen.0030108. Epub 2007 May 16. PLoS Genet. 2007. PMID: 17590087 Free PMC article.
The roles of kinases in familial Parkinson's disease.
Cookson MR, Dauer W, Dawson T, Fon EA, Guo M, Shen J. Cookson MR, et al. J Neurosci. 2007 Oct 31;27(44):11865-8. doi: 10.1523/JNEUROSCI.3695-07.2007. J Neurosci. 2007. PMID: 17978026 Free PMC article. Review.
335 results