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INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors.
Li Q, Jiang B, Guo J, Shao H, Del Priore IS, Chang Q, Kudo R, Li Z, Razavi P, Liu B, Boghossian AS, Rees MG, Ronan MM, Roth JA, Donovan KA, Palafox M, Reis-Filho JS, de Stanchina E, Fischer ES, Rosen N, Serra V, Koff A, Chodera JD, Gray NS, Chandarlapaty S. Li Q, et al. Among authors: koff a. Cancer Discov. 2022 Feb;12(2):356-371. doi: 10.1158/2159-8290.CD-20-1726. Epub 2021 Sep 20. Cancer Discov. 2022. PMID: 34544752 Free PMC article.
ZIC1 overexpression is oncogenic in liposarcoma.
Brill E, Gobble R, Angeles C, Lagos-Quintana M, Crago A, Laxa B, Decarolis P, Zhang L, Antonescu C, Socci ND, Taylor BS, Sander C, Koff A, Singer S. Brill E, et al. Among authors: koff a. Cancer Res. 2010 Sep 1;70(17):6891-901. doi: 10.1158/0008-5472.CAN-10-0745. Epub 2010 Aug 16. Cancer Res. 2010. PMID: 20713527 Free PMC article.
TRIM3, a tumor suppressor linked to regulation of p21(Waf1/Cip1.).
Liu Y, Raheja R, Yeh N, Ciznadija D, Pedraza AM, Ozawa T, Hukkelhoven E, Erdjument-Bromage H, Tempst P, Gauthier NP, Brennan C, Holland EC, Koff A. Liu Y, et al. Among authors: koff a. Oncogene. 2014 Jan 16;33(3):308-15. doi: 10.1038/onc.2012.596. Epub 2013 Jan 14. Oncogene. 2014. PMID: 23318451 Free PMC article.
Progression-Free Survival Among Patients With Well-Differentiated or Dedifferentiated Liposarcoma Treated With CDK4 Inhibitor Palbociclib: A Phase 2 Clinical Trial.
Dickson MA, Schwartz GK, Keohan ML, D'Angelo SP, Gounder MM, Chi P, Antonescu CR, Landa J, Qin LX, Crago AM, Singer S, Koff A, Tap WD. Dickson MA, et al. Among authors: koff a. JAMA Oncol. 2016 Jul 1;2(7):937-40. doi: 10.1001/jamaoncol.2016.0264. JAMA Oncol. 2016. PMID: 27124835 Free PMC article. Clinical Trial.
135 results