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A single-cell tumor immune atlas for precision oncology.
Nieto P, Elosua-Bayes M, Trincado JL, Marchese D, Massoni-Badosa R, Salvany M, Henriques A, Nieto J, Aguilar-Fernández S, Mereu E, Moutinho C, Ruiz S, Lorden P, Chin VT, Kaczorowski D, Chan CL, Gallagher R, Chou A, Planas-Rigol E, Rubio-Perez C, Gut I, Piulats JM, Seoane J, Powell JE, Batlle E, Heyn H. Nieto P, et al. Among authors: trincado jl. Genome Res. 2021 Oct;31(10):1913-1926. doi: 10.1101/gr.273300.120. Epub 2021 Sep 21. Genome Res. 2021. PMID: 34548323 Free PMC article.
Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment.
Rubio-Perez C, Planas-Rigol E, Trincado JL, Bonfill-Teixidor E, Arias A, Marchese D, Moutinho C, Serna G, Pedrosa L, Iurlaro R, Martínez-Ricarte F, Escudero L, Cordero E, Cicuendez M, Ruiz S, Parra G, Nuciforo P, Gonzalez J, Pineda E, Sahuquillo J, Tabernero J, Heyn H, Seoane J. Rubio-Perez C, et al. Among authors: trincado jl. Nat Commun. 2021 Mar 8;12(1):1503. doi: 10.1038/s41467-021-21789-x. Nat Commun. 2021. PMID: 33686071 Free PMC article.
Converging and evolving immuno-genomic routes toward immune escape in breast cancer.
Blanco-Heredia J, Souza CA, Trincado JL, Gonzalez-Cao M, Gonçalves-Ribeiro S, Gil SR, Pravdyvets D, Cedeño S, Callari M, Marra A, Gazzo AM, Weigelt B, Pareja F, Vougiouklakis T, Jungbluth AA, Rosell R, Brander C, Tresserra F, Reis-Filho JS, Tiezzi DG, de la Iglesia N, Heyn H, De Mattos-Arruda L. Blanco-Heredia J, et al. Among authors: trincado jl. Nat Commun. 2024 Feb 21;15(1):1302. doi: 10.1038/s41467-024-45292-1. Nat Commun. 2024. PMID: 38383522 Free PMC article.
Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells.
Velasco-Hernandez T, Trincado JL, Vinyoles M, Closa A, Martínez-Moreno A, Gutiérrez-Agüera F, Molina O, Rodríguez-Cortez VC, Ximeno-Parpal P, Fernández-Fuentes N, Petazzi P, Beneyto-Calabuig S, Velten L, Romecin P, Casquero R, Abollo-Jiménez F, de la Guardia RD, Lorden P, Bataller A, Lapillonne H, Stam RW, Vives S, Torrebadell M, Fuster JL, Bueno C, Sarry JE, Eyras E, Heyn H, Menéndez P. Velasco-Hernandez T, et al. Among authors: trincado jl. Hemasphere. 2024 Feb 26;8(2):e45. doi: 10.1002/hem3.45. eCollection 2024 Feb. Hemasphere. 2024. PMID: 38435427 Free PMC article.
β-Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T-cell acute lymphoblastic leukemia.
García-Hernández V, Arambilet D, Guillén Y, Lobo-Jarne T, Maqueda M, Gekas C, González J, Iglesias A, Vega-García N, Sentís I, Trincado JL, Márquez-López I, Heyn H, Camós M, Espinosa L, Bigas A. García-Hernández V, et al. Among authors: trincado jl. EMBO Mol Med. 2023 Feb 8;15(2):e16554. doi: 10.15252/emmm.202216554. Epub 2023 Jan 4. EMBO Mol Med. 2023. PMID: 36597789 Free PMC article.
Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high-hyperdiploid B-cell acute lymphoblastic leukemia.
Ramos-Muntada M, Trincado JL, Blanco J, Bueno C, Rodríguez-Cortez VC, Bataller A, López-Millán B, Schwab C, Ortega M, Velasco P, Blanco ML, Nomdedeu J, Ramírez-Orellana M, Minguela A, Fuster JL, Cuatrecasas E, Camós M, Ballerini P, Escherich G, Boer J, DenBoer M, Hernández-Rivas JM, Calasanz MJ, Cazzaniga G, Harrison CJ, Menéndez P, Molina O. Ramos-Muntada M, et al. Among authors: trincado jl. Mol Oncol. 2022 Aug;16(16):2899-2919. doi: 10.1002/1878-0261.13276. Epub 2022 Jul 19. Mol Oncol. 2022. PMID: 35726693 Free PMC article.
ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer.
Trincado JL, Reixachs-Solé M, Pérez-Granado J, Fugmann T, Sanz F, Yokota J, Eyras E. Trincado JL, et al. PLoS Comput Biol. 2021 Sep 16;17(9):e1009411. doi: 10.1371/journal.pcbi.1009411. eCollection 2021 Sep. PLoS Comput Biol. 2021. PMID: 34529669 Free PMC article.
17 results